Mechanistic links between diet, lipid metabolism, and tumor growth and progression (U01 Clinical Trial Not Allowed)
ID: 356922Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356922

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PAR-25-119.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Mechanistic links between diet, lipid metabolism, and tumor growth and progression (U01 Clinical Trial Not Allowed)" aimed at advancing research in the intersection of nutrition and cancer biology. This initiative seeks applications that investigate the molecular mechanisms by which lipid metabolism influences tumor dynamics, particularly focusing on the effects of dietary lipids and their interactions with the tumor microenvironment. The program is designed to bridge the fields of nutrition and cancer research, with a budget cap of $500,000 per year for up to five years, encouraging innovative studies, especially those involving high-fat or ketogenic diets. Interested applicants can find more information and application guidelines at the provided NIH link, with a submission deadline of October 23, 2025, and inquiries directed to grantsinfo@nih.gov.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PAR-25-119.html
    The National Cancer Institute (NCI) is announcing a funding opportunity focused on research investigating the mechanistic links between diet, lipid metabolism, and tumor growth and progression, under the U01 Clinical Trial Not Allowed cooperative agreement. The program seeks applications that define the molecular mechanisms through which lipid metabolism affects tumors, particularly emphasizing the impact of dietary influences. Key research areas include understanding how various dietary lipids affect tumor dynamics and the interactions between diet and the tumor microenvironment. The funding, which includes a budget cap of $500,000 per year for up to five years, will support projects that bridge the fields of nutrition and cancer research. Applications are encouraged especially for studies involving high-fat or ketogenic diets, even if direct clinical translation is not required. Investigators must adhere to stringent application requirements and demonstrate adequate expertise in nutrition. Outcomes from this initiative are expected to stimulate scientific understanding and potentially lead to novel therapeutic strategies. The program prioritizes significant innovation and rigorous methodologies, while non-responsive projects, particularly those not focused on fundamental investigations, will face disqualification. The announcement includes important dates, eligibility requirements, and application guidelines for interested institutions and researchers.
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