Facilitating T1 Translational Aging Research: Preclinical and Early Phase Human Studies (UG3/UH3 Clinical Trial Optional)
ID: 356873Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/356873

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-25-027.html
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for the Facilitating T1 Translational Aging Research funding opportunity, aimed at advancing new therapeutics for aging-related conditions through preclinical and early-phase human studies. This initiative focuses on two main project categories: traditional drug development and data-driven computational drug repurposing strategies, with the UG3 phase supporting planning and preliminary studies for up to two years, followed by the UH3 phase for implementation activities lasting up to three years. The funding opportunity is significant for improving health outcomes for older adults, with a total anticipated funding of $2.5 million available for up to five awards, and applications are due by January 10, 2025. Interested applicants can find more information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-AG-25-027-Full-Announcement.html
    RFA-AG-25-027.html
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is inviting applications for funding to support T1 translational aging research, aimed at advancing new therapeutics for aging-related conditions. This opportunity focuses on two project categories: traditional drug development and data-driven computational drug repurposing strategies. The UG3 phase will fund planning and preliminary studies for up to two years, followed by the UH3 phase, which can last up to three years for implementation activities. While this initiative encourages innovation by integrating computational approaches into drug development, it excludes applications concerning neurodegenerative diseases and Alzheimer’s-related conditions. A total of $2.5 million is anticipated for up to five awards, with specific budget caps for each phase. Eligible applicants include educational institutions, non-profit organizations, and government agencies. Applications must comply with stringent guidelines, including specified milestones and timelines, and will undergo rigorous peer review before potential funding decisions. This funding opportunity reflects a commitment to improving health outcomes for older adults through novel therapeutic approaches in aging research.
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