The Agency for Healthcare Research and Quality (AHRQ) is offering the Mentored Career Enhancement Awards for Established Investigators in Patient-Centered Outcome Research (K18), aimed at mid-career and senior researchers looking to enhance their skills in comparative effectiveness research methodology. This grant program encourages applicants to dedicate at least 50% of their professional effort to patient-centered outcomes research (PCOR) over a project period of six to twenty-four months, with a budget of up to $275,000 annually per award, which includes salary and related expenses. The initiative particularly seeks applications from institutions serving racial and ethnic minority populations, emphasizing the importance of equitable healthcare access and quality improvements. Interested applicants can reach out to Grant_Queries@ahrq.hhs.gov for further information, and the application deadline is July 12, 2025.