Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) (R01 Clinical Trial Not Allowed)
ID: 357191Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/357191

Additional Information

http://grants.nih.gov/grants/guide/pa-files/PA-25-174.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity titled "Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE)" aimed at advancing cancer therapeutics through research projects that utilize radionuclide-based therapies. This initiative specifically seeks R01 research proposals that investigate the effects of various radiation types on normal tissues, tumor cells, and the tumor microenvironment, with a focus on novel targeting strategies and pharmacodynamic biomarkers. The STRIPE program is critical for enhancing the understanding of radiopharmaceuticals in cancer treatment, with applications limited to direct costs of $500,000 per year and a maximum project duration of five years. Interested applicants must adhere to NIH guidelines, with submission deadlines starting January 5, 2025, and can direct inquiries to grantsinfo@nih.gov for further information.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    PA-25-174-Full-Announcement.html
    PA-25-174.html
    The National Cancer Institute (NCI) is soliciting applications for the Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) program, aiming to advance cancer therapeutics utilizing radionuclide-based therapies. This funding opportunity specifically seeks R01 research projects focused on understanding the effects of various radiation types on normal tissues, tumor cells, and the tumor microenvironment. Key research areas include examining novel RPT targeting strategies, pharmacodynamic biomarkers, and understanding the biological effects of RPT on both cancer and normal tissues. Applications must not propose clinical trials and are limited to direct costs of $500,000 per year, with a maximum project period of five years. Eligible applicants encompass a wide range of organizations, including educational institutions and non-profits. The application process demands adherence to strict NIH guidelines, with critical dates for submission beginning January 5, 2025, and expected funding announcements following peer review and advisory council assessment. Ultimately, the STRIPE initiative is designed to foster collaborative preclinical studies that will guide the future development and translation of radionuclide therapies to clinical applications, addressing significant gaps in the current understanding of radiopharmaceuticals in cancer treatment.
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