The federal grant notice titled "Resilient Systems Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health" is seeking solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSO's interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care. The grant is open to small businesses and does not require cost sharing or matching. The funding instrument type is "Other" and the category of funding activity is "Science and Technology and other Research and Development". The opportunity is posted under the discretionary category and falls under CFDA number 93.384. The close date for submissions is March 14, 2025. The expected number of awards is 100. The grant description highlights the need for innovations that enhance the adaptability, reliability, and interoperability of the health ecosystem. The grant is particularly interested in innovations that foster flexibility and enable adaptation to system stressors, with the goal of delivering high-quality care and improving health outcomes. The grant seeks proposals in three interest areas: Sociotechnical System Innovation, Health Ecosystem Integration, and Adaptive & Antifragile Solutions. Proposals should use innovative approaches to enable revolutionary advances in science, technology, systems, or methodology. Proposals that represent an evolutionary or incremental advance in the state of the art or technology that has reached the clinical trial stage are excluded. The grant does not support proposals directed towards policy changes, traditional education and training, or center coordination, formation, or development, and construction of physical infrastructure. For more information and to submit proposals, interested parties can visit the additional information URL provided.