Resilient Systems Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
ID: 352988Type: Posted
Overview

Buyer

Advanced Research Projects Agency for Health (HHS-ARPAH)

Eligible Applicants

Small Businesses

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Other

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The Advanced Research Projects Agency for Health (ARPA-H) is inviting small businesses to submit proposals for innovative solutions aimed at addressing systemic challenges in healthcare through its Resilient Systems Office initiative. The agency seeks groundbreaking research and development projects that enhance the adaptability, reliability, and interoperability of the health ecosystem, focusing on areas such as sociotechnical system innovation, health ecosystem integration, and adaptive solutions to improve health outcomes. This opportunity is critical for advancing healthcare innovations and addressing long-standing gaps in care quality and accessibility. Proposals are due by March 14, 2025, with an expected 100 awards available, and interested applicants can reach out to Mark Baxter at mark.baxter@arpa-h.gov for further information.

    Point(s) of Contact
    Files
    Title
    Posted
    The Administrative & National Policy Requirements document outlines essential submission guidelines for proposal volume one, emphasizing formatting, format types, and required content. It includes sections for team member identification, conflict of interest disclosures, research security, intellectual property, and compliance with human and animal subjects research requirements. Additionally, it mandates the inclusion of management plans for Controlled Unclassified Information and representations regarding unpaid tax liabilities or felony convictions.
    The Administrative and National Policy Requirements document serves as a guide for proposal submissions, requiring detailed information on team members, conflict of interest disclosures, and various research considerations. It specifies formatting requirements, types of acceptable file formats, and mandates thorough documentation concerning intellectual property, human and animal research, and compliance with federal laws. Additionally, it stresses the importance of managing Controlled Unclassified Information (CUI) and includes a section for representations regarding tax liabilities and felony convictions.
    The Cost Proposal requires proposers to submit a narrative and a cost spreadsheet detailing all cost components relevant to their project, including equipment purchases and justifications for significant cost drivers. Each submission must adhere to specific formatting requirements and include sections on various cost factors such as level of effort, materials, travel, and others, with particular emphasis on supporting documentation for costs exceeding certain thresholds. Additionally, proposers are to engage in value analysis to identify potential cost reductions that do not compromise project outcomes.
    The Cost Proposal requires proposers to submit a narrative and supporting documentation detailing project costs, formatted on standard paper with specific margins and font size. Key components include outlining the level of effort, materials, equipment purchases, travel costs, other direct costs, and consultant/subawardee expenses, with an emphasis on substantiating significant cost drivers. Proposers must also detail any cost-sharing arrangements and provide a value analysis for cost reductions that do not adversely impact project outcomes.
    This document provides detailed instructions for completing a cost proposal spreadsheet, emphasizing the necessity of data entry in green-filled cells and its sequential completion starting with the Proposal Data tab. It outlines the structure of the spreadsheet, which includes a Base tab and two Option tabs for multiple time periods, along with specific instructions on how to input labor and indirect rates, travel details, and other direct costs. All required fields are specified to streamline the calculation of totals and ensure accurate data aggregation across various sections.
    The document outlines an Other Transaction Agreement (OTA) between the Advanced Research Projects Agency for Health (ARPA-H) and a potential performer, aimed at facilitating a coordinated research and development program. It details the agreement's structure, including articles on intellectual property rights, project management, payment schedules for milestones, and compliance with federal regulations concerning human and animal subjects, data rights, and research ethics. The agreement also emphasizes the roles and responsibilities of both parties, including requirements for reporting and dispute resolution procedures.
    The "Other Transaction Agreement" between a potential performer and the Advanced Research Projects Agency for Health (ARPA-H) outlines a collaborative program focused on critical technology development in health care, with a term of 36 months and a structured payment system based on milestone completion. Key provisions address intellectual property rights, project management, financial responsibilities, and compliance with regulations involving human and animal research. The agreement emphasizes continuous government involvement and a commitment to good faith in achieving project goals.
    The Task Description Document (TDD) outlines a structured template for detailing project tasks/subtasks, including objectives, approaches, and milestones, while identifying responsible organizations and any involvement of human subjects or animals. Each subtask requires concise descriptions, location identification (e.g., university campus), and clearly defined deliverables and related milestones. The document emphasizes compliance with guidelines and encourages thorough breakdowns to enhance task clarity and accountability.
    The Task Description Document (TDD) provides a structured template for detailing project tasks and their execution while ensuring compliance with organizational standards. It requires comprehensive task breakdowns, identification of responsible organizations, measurable milestones, and deliverables, along with considerations for human or animal subjects where applicable. The document emphasizes clarity and thoroughness in documenting project objectives, approaches, and locations of work.
    The document outlines the requirements for submitting a Technical and Management Volume proposal, specifying formats, page limits, and content structure, including a 20-page limit for the proposal while excluding supplementary documents. Proposers must provide specific examples and avoid extraneous materials beyond stated criteria, with emphasis on innovative claims, project goals, technical plans, and team capabilities. A clear and concise presentation is expected, focusing on unique approaches and measurable milestones to assess project success and impact on health outcomes.
    The document outlines requirements for a Technical and Management Volume proposal submission, specifying that it must be in certain formats, adhere to a 20-page limit, and follow formatting guidelines including font size and margin specifications. It emphasizes concise, specific content over generalities, and details what is included and excluded in the page limit while also encouraging the use of an Innovative Claims Table to clearly present the uniqueness and benefits of the proposed project. Proposals must also articulate technical challenges, a credible project plan, team capabilities, and include a bibliography of relevant qualifications and references.
    The Task Description Document (TDD) outlines a structured approach for defining tasks related to a proposed project, emphasizing the importance of detailing objectives, methodologies, responsible organizations, and milestones. Each task includes specific components regarding human or animal subjects, university locations, and expected deliverables. The overall aim is to facilitate clear communication and measurable progress tracking throughout the project lifecycle.
    Similar Opportunities
    Health Science Futures: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
    Active
    Advanced Research Projects Agency for Health
    The Advanced Research Projects Agency for Health (ARPA-H) is inviting proposals for the "Health Science Futures: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health" federal grant. This opportunity aims to support groundbreaking research projects that develop innovative technologies, tools, and platforms to address significant healthcare challenges and improve health outcomes across a wide range of diseases. Eligible applicants, specifically small businesses, are encouraged to submit solution summaries and proposals that align with the ARPA-H mission, focusing on transformative technologies, tools, and adaptable systems that can lead to revolutionary advances in medicine and healthcare. The grant does not require cost-sharing or matching, with an expected 100 awards available, and proposals are due by March 14, 2025. For further inquiries, interested parties can contact Mark Baxter at mark.baxter@arpa-h.gov or by phone at 301-827-4852.
    Scalable Solutions Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
    Active
    Advanced Research Projects Agency for Health
    The Advanced Research Projects Agency for Health (ARPA-H) is inviting proposals for the "Scalable Solutions Office: Office-Wide Innovative Solutions," aimed at enhancing healthcare access and affordability through innovative research and development projects. Proposals should focus on scalable technologies and interventions, collaborative distribution networks, and biomanufacturing innovations that address healthcare disparities, particularly in underserved communities. This initiative is critical for developing solutions that can be rapidly deployed and adapted to various contexts, ultimately improving health outcomes across diverse populations. Interested small businesses must submit their proposals by March 14, 2025, and can contact Mark Baxter at mark.baxter@arpa-h.gov for further information.
    Proactive Health Office: Office-Wide Innovative Solutions Opening for Advanced Research Projects Agency for Health
    Active
    Advanced Research Projects Agency for Health
    The Advanced Research Projects Agency for Health (ARPA-H) is inviting proposals for the "Proactive Health Office: Office-Wide Innovative Solutions Opening," aimed at advancing research projects that enhance health outcomes and healthspan for Americans. The initiative seeks innovative solutions focused on disease prevention, early detection methods, and system-level innovations to promote proactive health behaviors and interventions. This opportunity is particularly significant as it addresses the need for a shift from reactive medical treatments to proactive health strategies, emphasizing the importance of improving overall public health. Proposals are due by March 14, 2025, and interested applicants, specifically small businesses, can reach out to Mark Baxter at mark.baxter@arpa-h.gov for further information. Additional details can be found at the provided link.
    Groundbreaking Lymphatic Interventions and Drug Exploration
    Active
    Advanced Research Projects Agency for Health
    The Advanced Research Projects Agency for Health (ARPA-H) is inviting proposals for the Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE) Program through a DRAFT Innovative Solutions Opening (ISO) ARPA-H-SOL-24-111. This initiative aims to foster innovative solutions in lymphatic health and drug exploration, encouraging small businesses to participate and contribute to groundbreaking research and development in this critical area. The funding opportunity has an award ceiling of $50 million and a minimum award floor of $1, with no cost-sharing or matching requirements. Interested applicants should note that the proposal submission deadline is October 31, 2024, and can reach out to the GLIDE Team at GLIDE@arpa-h.gov for further inquiries. Additional details can be found on the SAM.gov posting.
    Master Announcement Instructions (MAI)
    Active
    Advanced Research Projects Agency for Health
    The Advanced Research Projects Agency for Health (ARPA-H) has announced the Master Announcement Instructions (MAI), a federal grant opportunity aimed at establishing standardized tiered proposal submission requirements for research and development projects. This initiative seeks to streamline the proposal process, reducing the upfront work required for cost information submissions, thereby lowering barriers for non-traditional performers such as universities, non-profit organizations, and small businesses. Proposals must be submitted against specific Module Announcements linked to the MAI, as submissions directly against the MAI are not permitted. Interested applicants should note that the deadline for submissions is October 20, 2024, and can direct inquiries to the MAI Team at MAIQuestions@arpa-h.gov for further information.
    Ensuring Research Integrity - Research on Research Integrity (RRI)
    Active
    Office of the Assistant Secretary for Health
    The Office of the Assistant Secretary for Health is forecasting a federal grant opportunity titled "Ensuring Research Integrity - Research on Research Integrity (RRI)." This initiative aims to enhance the quality and integrity of biomedical and behavioral research by funding projects that investigate the root causes of research misconduct and the factors that promote research integrity. The grant will support social and behavioral research focusing on various aspects, including institutional culture, policy effectiveness, and reporting mechanisms, with a total estimated funding of $500,000 available for two awards, each ranging from $150,000 to $250,000. Interested small businesses and other eligible entities are encouraged to submit applications electronically by April 8, 2025, with the anticipated award date set for July 1, 2025. For further inquiries, applicants may contact Armineh Ghazarian at Armineh.Ghazarian@hhs.gov or by phone at 240-453-8200.
    Airman Readiness Medical Research (ARMR) Hybrid BAA
    Active
    Air Force -- Research Lab
    The Air Force Research Laboratory (AFRL) is soliciting proposals for the Airman Readiness Medical Research (ARMR) program through a Hybrid Broad Agency Announcement (BAA) designated FA8650-20-S-6008. The primary objectives of this initiative are to conduct medical research aimed at optimizing the health and performance of Airmen, focusing on ensuring medical availability and understanding the effects of various operational environments on Airman well-being. This program is critical for enhancing the operational readiness of military personnel, particularly in high-demand mission scenarios, with key research areas including aeromedical evacuation, cognitive performance, and exposure health. The total funding available for this program is estimated at $480 million, with individual awards ranging from $50,000 to $49 million. Interested parties are encouraged to submit white papers by May 1, 2025, and can direct inquiries to Amber A. Taylor at amber.taylor.9@us.af.mil.
    Ensuring Research Integrity - Program Development and Evaluation Program (PDE)
    Active
    Office of the Assistant Secretary for Health
    The Office of the Assistant Secretary for Health is forecasting a federal grant opportunity titled "Ensuring Research Integrity - Program Development and Evaluation Program (PDE)." This initiative aims to fund projects that develop and implement innovative approaches and tools to promote research integrity and prevent misconduct, including educational resources, risk assessment tools, and intervention programs. The importance of this funding lies in its potential to enhance ethical research practices and foster a culture of integrity within research environments. The estimated total program funding is $150,000, with individual awards ranging from $50,000 to $75,000, and applications are expected to be submitted electronically by April 10, 2025. For further inquiries, interested parties can contact Armineh Ghazarian at Armineh.Ghazarian@hhs.gov or by phone at 240-453-8200.
    Military Health System Research Program Notice of Funding Opportunity
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), has announced a Notice of Funding Opportunity (NOFO) for the Military Health System Research Program (MHSRP), aimed at enhancing research capabilities within the Military Health System (MHS). This program invites applications for research projects that focus on healthcare economics, quality, outcomes, variations, health readiness, and the impacts of policy changes, with the goal of fostering innovative health system research that supports both military and civilian healthcare. The total estimated funding for this initiative is $10 million, with applications due by September 20, 2024, following a Letter of Intent submission by June 10, 2024. Interested applicants can reach out to the DHA MHSR Program Mailbox at dha.ncr.j-9.mbx.hsr@health.mil for further information.
    Telehealth Rapid Response Center
    Active
    Health Resources and Services Administration
    The Health Resources and Services Administration (HRSA) is forecasting a federal grant opportunity titled "Telehealth Rapid Response Center." This initiative aims to conduct rapid data analyses and short-term telehealth research studies to enhance understanding of the impact of policies and regulations, ultimately improving telehealth access for underserved populations in the United States. The program is critical for addressing health disparities and ensuring equitable access to telehealth services. The estimated total program funding is $1,900,000, with two awards expected. Interested applicants, including domestic public, non-profit, and for-profit entities, can reach out to Whitney Wiggins at wwiggins@hrsa.gov or (301) 443-4966 for further information. The synopsis is expected to be posted on January 24, 2025, with a closing date of April 24, 2025, and project start date anticipated for September 1, 2025.