The Substance Abuse and Mental Health Services Administration (SAMHSA) is offering a federal grant opportunity titled "Tribal Behavioral Health: Substance Use Prevention," aimed at enhancing substance use and overdose prevention activities within American Indian and Alaska Native communities. This program seeks to establish effective prevention systems that increase protective factors, address the interplay between suicide and substance use, and develop sustainable infrastructure for long-term change. With an estimated total program funding of $2,000,000 and an expected six awards, eligible applicants include federally recognized AI/AN tribes, tribal organizations, Urban Indian Organizations, and consortia of tribes or tribal organizations. Interested parties can reach out to Shannon Hastings at (240) 276-1869 or via email at DTPNOFO@samhsa.hhs.gov for further information, with the synopsis expected to be posted on May 1, 2025.