ML/AI Tools to Advance Genomic Translational Research (MAGen) - Coordinating Center (UG3/UH3, Clinical Trials Not Allowed)
ID: 354156Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $800K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for the Coordinating Center of the ML/AI Tools to Advance Genomic Translational Research (MAGen) Consortium. This initiative aims to develop machine learning (ML) and artificial intelligence (AI) tools to enhance the prediction of disease manifestation from pathogenic genetic variants, while also addressing the ethical, legal, and social implications (ELSI) of integrating these technologies into genomic medicine. The program is structured in two phases: the UG3 phase focuses on designing a consortium-wide framework, and the UH3 phase emphasizes implementing these frameworks and resources. Eligible applicants include higher education institutions, nonprofits, and government organizations, with a budget of up to $800,000 per year for five years, totaling an anticipated investment of $1.2 million for one award. Applications are due by July 29, 2024, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.

    Point(s) of Contact
    Files
    Title
    Posted
    The National Institutes of Health (NIH) is inviting applications for the Coordinating Center of the ML/AI Tools to Advance Genomic Translational Research (MAGen) Consortium. This initiative aims to develop machine learning (ML) and artificial intelligence (AI) tools that enhance the prediction of disease manifestation from pathogenic genetic variants. The Coordinating Center will facilitate collaboration among diverse teams to support research activities related to the deployment and validation of these tools, while also addressing the ethical, legal, and social implications (ELSI) of integrating ML/AI into genomic medicine. The program has a two-phase structure: the UG3 phase will involve designing a consortium-wide framework, while the UH3 phase will focus on implementing these frameworks and resources. The budget for a successful application is limited to $800,000 per year for five years, with an anticipated total investment of $1.2 million for one award. Eligible applicants include higher education institutions, nonprofits, and government organizations. The call for applications is positioned within the context of advancing genomic medicine, enhancing predictive capabilities in healthcare, and ensuring responsible management and sharing of genomic data. Applications are due by July 29, 2024, with two phases emphasizing strategic planning and execution in genomic research collaboration.
    Similar Opportunities
    Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed)" aimed at developing informatics tools that enhance the use of a human pangenome reference as part of the Human Genome Reference Program (HGRP). The initiative seeks to fund projects that create broadly applicable tools for various sectors of genomics, including clinical and functional genomics, with a focus on improving analytical capabilities over existing methods. Up to $4 million will be allocated to support approximately six projects over a maximum period of three years, with individual project budgets capped at $400,000 annually. Interested applicants can find more information and submit inquiries via email to grantsinfo@nih.gov, with the application deadline set for March 3, 2025.
    Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity for the Centers of Excellence in Genomic Science (CEGS) program, aimed at supporting innovative, interdisciplinary research in genomic science. This program seeks to establish academic centers that will develop transformative genomic approaches to address significant biomedical challenges, with a focus on integrating advanced technological and computational methods. Each award can provide up to $1.5 million per year for a maximum of five years, with potential renewal for an additional five years, and applications are due by June 23, 2025. Eligible applicants include a range of institutions such as higher education entities, nonprofits, and various government organizations, while foreign entities are not eligible. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.
    Advancing Genomic Medicine Research (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting proposals for the "Advancing Genomic Medicine Research (R01 Clinical Trial Optional)" grant, aimed at stimulating innovative research in the implementation of genomic technologies in clinical care. This funding opportunity emphasizes addressing health disparities and requires applicants to develop a Plan for Enhancing Diverse Perspectives to ensure inclusivity in research teams and participant recruitment. The initiative seeks to explore the value of genomic data in improving clinical outcomes, identify barriers to implementation, and develop effective data-sharing methods, with approximately $2.4 million available for three awards and an additional $700,000 for one award in fiscal year 2024. Applications are due by February 12, 2025, and interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Advancing Genomic Medicine Research (R01 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a funding opportunity titled "Advancing Genomic Medicine Research (R01 Clinical Trial Optional)" aimed at enhancing the use and sharing of genomic information in clinical care across diverse populations. This initiative seeks proposals that focus on understanding the implementation of genomic medicine, addressing barriers to access, and developing analytical tools for clinical genomic data, with a strong emphasis on inclusivity for populations experiencing health disparities. The NIH has allocated approximately $2.4 million for three projects, with an additional project funded by the National Cancer Institute, and applicants are required to submit a Plan for Enhancing Diverse Perspectives (PEDP) as part of their proposals. Interested parties must submit their applications by February 11, 2025, and can direct inquiries to grantsinfo@nih.gov for further information.
    Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)" aimed at stimulating innovation in the implementation and sharing of genomic information in clinical care across diverse populations. This initiative encourages applications for small research projects that explore the integration of genomic data into clinical practice, assess barriers to implementation, and develop innovative data analysis techniques, particularly focusing on underrepresented populations in genomic research. The maximum budget for each application is $50,000 over a two-year period, with a total funding expectation of approximately $150,000 for FY 2024. Interested applicants must submit their proposals by February 12, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Advancing Genomic Medicine Research (R21 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Advancing Genomic Medicine Research (R21 Clinical Trial Optional)" aimed at stimulating innovation in the application of genomic information in clinical care, particularly for populations experiencing health disparities. The initiative seeks to enhance understanding of how to effectively implement and share genomic technologies across diverse communities, including racial and ethnic minorities, underserved rural populations, and sexual and gender minority groups. With an expected total funding of approximately $1.5 million for fiscal year 2024, individual project budgets may reach up to $250,000. Interested applicants must submit their proposals by February 11, 2025, and can find additional details and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering funding through the opportunity titled "ClinGen Genomic Curation Expert Panels (U24 Clinical Trial Not Allowed)" to establish Expert Panels focused on the clinical relevance of genetic variants. The primary objective of this initiative is to develop a comprehensive knowledge base that enhances the interpretation of genes and genomic variants associated with high-priority diseases, utilizing established tools and resources from the Clinical Genomics Resource (ClinGen) and ClinVar. This funding is crucial for advancing genomic research and improving clinical outcomes through precision medicine, with a maximum award ceiling of $220,000 per year for a grant period of up to three years. Interested applicants must submit their proposals by May 25, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Advancing Genomic Medicine Research (R21 Clinical Trial Optional)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Advancing Genomic Medicine Research (R21 Clinical Trial Optional)" aimed at stimulating innovative research in the integration of genomic information into clinical care, particularly for populations experiencing health disparities. This initiative encourages proposals that address implementation science, barriers to genomic medicine, and the integration of genomic data with health and social determinants, with a focus on enhancing health equity among underrepresented groups. The grant provides funding up to $250,000, with applications open from November 1, 2023, until the close date of February 11, 2025. Interested applicants can find more information and application guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)" aimed at stimulating innovation in the implementation and sharing of genomic information in clinical care across diverse populations. This initiative seeks proposals that enhance understanding of genomic data applications, assess implementation methods, and identify barriers to health equity, particularly for underrepresented groups. The R03 grant mechanism supports small research projects with a maximum budget of $50,000 per year, with an estimated total funding of approximately $150,000 for two awards in fiscal year 2024. Applications must be submitted electronically by February 12, 2025, and interested parties can contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
    Active
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)" aimed at supporting innovative research in computational genomics and data science. This initiative encourages applications that focus on developing novel analytical methodologies, tools, and software that can be broadly applied to enhance human health and disease understanding, with an emphasis on scalable systems for managing complex genomic data. Eligible applicants include a wide range of organizations such as higher education institutions, nonprofits, and tribal colleges, with a maximum budget of $500,000 per year available for projects lasting up to five years. The application submission period opens on January 6, 2025, and closes on September 7, 2027. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov.