The National Institutes of Health (NIH) is offering the Support for Research Excellence – First Independent Research (SuRE-First) Award, a federal grant aimed at enhancing biomedical research capacity at resource-limited higher education institutions. This program specifically targets faculty investigators who have not previously received independent external research grants, providing funding to support investigator-initiated research while also fostering quality research experiences for students. The SuRE-First awards, which promote diversity through a required Plan for Enhancing Diverse Perspectives (PEDP), offer up to $125,000 per year for a maximum of four years to eligible institutions, including those with significant Pell grant enrollment. Interested applicants must adhere to strict submission guidelines and submit their applications by January 7, 2027. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information page at https://grants.nih.gov/grants/guide/pa-files/PAR-24-145.html.