The Department of Energy's Office of Science is inviting applications for the funding opportunity titled "Systems Biology Research to Advance Bioenergy Crop Production" (NOFO Number DE-FOA-0003453). This initiative seeks to enhance understanding of the molecular mechanisms that influence bioenergy feedstock productivity and the role of microbial communities in supporting plant vigor, particularly under suboptimal environmental conditions. The program aims to contribute to the development of sustainable bioenergy systems by addressing critical knowledge gaps in bioenergy crop performance, ultimately supporting the United States' energy and environmental security goals. The total funding available is up to $75 million, with individual awards ranging from $5 million to $15 million, and applications are due by March 26, 2025. Interested applicants can reach out to SC.GrantsandContracts@science.doe.gov for further information.