Hermes
ID: 353643Type: Posted
Overview

Buyer

DARPA - Biological Technologies Office (DOD-DARPA-BTO)

Eligible Applicants

Others

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Procurement Contract

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The Defense Advanced Research Projects Agency (DARPA) is inviting innovative proposals for the Hermes program, which focuses on developing systemic drug delivery platforms for medical countermeasures (MCMs). The program seeks transformative approaches that ensure effective biodistribution, high endosomal escape efficiency, and low toxicity in the proposed delivery systems. Successful applicants will need to provide a comprehensive proposal detailing their delivery platform, including a screening pipeline, monitoring systems for biodistribution and expression, immunogenicity/toxicity assessment methods, and justification for the chosen therapeutic cargo. Proposals are due by June 11, 2024, at 4:00 PM ET, and interested parties can reach out to Dr. Shannon Greene at HermesBAA@darpa.mil for further inquiries. More information can be found on the SAM.gov Contract Opportunities website.

    Point(s) of Contact
    Files
    Title
    Posted
    Amendment 1 to HR001124S0025, pertaining to the Hermes Broad Agency Announcement, primarily aims to extend the deadline for full proposal submissions. The revised proposal due date is now set for June 11, 2024, at 4:00 PM ET, coinciding with the BAA closing date. This extension provides potential applicants additional time to prepare their proposals in response to the announcement. Such amendments are common in government RFPs and grants, allowing for increased participation and submission quality by accommodating the needs of applicants. This change underlines the government's commitment to an inclusive proposal process while maintaining necessary timelines for project initiation.
    Similar Opportunities
    Defense Sciences Office (DSO) Office-wide BAA
    DARPA - Defense Sciences Office
    The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals through its Defense Sciences Office (DSO) under the Broad Agency Announcement (BAA) HR001125S0013, aimed at advancing national security through revolutionary scientific and technological developments. Proposals should focus on groundbreaking research that leads to significant advancements rather than incremental improvements, covering areas such as materials, manufacturing, sensing, and intelligent systems. This initiative is crucial for fostering collaboration between government and private entities to enhance national security capabilities. Interested applicants can submit proposals until June 2, 2026, and are encouraged to contact the BAA Coordinator at HR001125S0013@darpa.mil for further information.
    DOD USAMRDC FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the U.S. Army Medical Research and Development Command (USAMRDC), has announced the FY23-FY27 Broad Agency Announcement (BAA) for Extramural Medical Research, which is open for submissions from October 1, 2022, to September 30, 2027. This opportunity invites innovative research proposals that address critical military medical challenges, particularly in the areas of Military Infectious Diseases, Combat Casualty Care, and Military Operational Medicine, with a focus on enhancing medical practices for both military personnel and civilians. The BAA emphasizes the importance of collaboration with Department of Defense and Department of Veterans Affairs resources and requires adherence to strict submission guidelines via Grants.gov and the electronic Biomedical Research Application Portal (eBRAP). Interested applicants can submit pre-proposals at any time during the five-year period, with full proposals invited based on initial submissions, and should direct inquiries to the CDMRP Help Desk at help@eBRAP.org.
    High-efficiency Nitrogen Oxidation (HNO3)
    DARPA - Defense Sciences Office
    The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals for the High-efficiency Nitrogen Oxidation (HNO3) initiative, aimed at developing decentralized nitric acid manufacturing technologies. This program seeks to address vulnerabilities in current production methods by enabling high-rate, energy-efficient nitric acid production from air and water, thereby enhancing the resilience of critical supply chains in the defense industrial base. Proposals should focus on revolutionary advancements in catalysts and reactor designs, with an emphasis on scalability and risk mitigation, culminating in a field demonstration of a full-scale prototype. Interested parties must submit their proposals by February 5, 2026, and can contact the BAA Coordinator at HNO3@darpa.mil for further information. Additional details can be found on the SAM.gov Contract Opportunities website.
    BROAD AGENCY ANNOUNCEMENT (BAA) for Extramural Biomedical and Human Performance Research and Development Department of Defense
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research Acquisition Activity (USAMRAA), has announced a Broad Agency Announcement (BAA) for Extramural Biomedical and Human Performance Research and Development. This opportunity invites unrestricted applicants to submit proposals aimed at advancing biomedical research and development, with a focus on enhancing human performance. The program is critical for fostering innovation in science and technology, particularly in areas that support the Department of Defense's mission. The estimated total program funding is $10 million, with individual awards ranging from $750,000 to $50 million, and proposals are due by July 31, 2028. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.
    TTO Office Wide (OW) BAA 2025
    DARPA - Tactical Technology Office
    The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals through the Tactical Technology Office (TTO) under the Broad Agency Announcement (BAA) HR001125S0011, titled "TTO Office Wide (OW) BAA 2025." This initiative aims to foster innovative solutions that enhance the U.S. military's operational capabilities in areas such as Design/Build/Buy, Surge and Sustain, Long Range Effects, and Disruptive Innovation. The BAA emphasizes the importance of developing revolutionary platforms and systems that can be rapidly adapted and sustained to meet national security needs. Interested parties must submit an Executive Summary by December 22, 2026, and can find additional details and submission guidelines on SAM.gov or by contacting the BAA Coordinator at HR001125S0011@darpa.mil.
    Fundamental Research to Counter Weapons of Mass Destruction
    Defense Threat Reduction Agency
    The Defense Threat Reduction Agency (DTRA) has announced a Broad Agency Announcement (BAA) for fundamental research aimed at countering Weapons of Mass Destruction (WMD), with funding available from October 1, 2024, to September 30, 2034. This opportunity invites proposals from accredited colleges, universities, and research entities to contribute to DTRA's mission of reducing WMD threats, emphasizing collaboration in areas such as chemical and biological defense. The funding will primarily be awarded as grants, with amounts ranging from $25,000 to $1 million annually, and proposals will undergo a two-phase evaluation process assessing scientific merit and mission relevance. Interested applicants should submit pre-application white papers and can direct inquiries to the BAA Administrative Mailbox at dtra.belvoir.rd.mbx.rd-cb-frbaa25-34-a@mail.mil before the closing date of September 30, 2034.
    Biological Threat Reduction with Global Partners Broad Agency Announcement (BAA)
    Defense Threat Reduction Agency
    The Defense Threat Reduction Agency (DTRA) has announced a Broad Agency Announcement (BAA) titled "Biological Threat Reduction with Global Partners," aimed at enhancing global health security against biological threats. This initiative invites submissions of Abstracts, White Papers, and Full Proposals from accredited universities, industry, and non-profit organizations to strengthen the capabilities of partner nations in preventing, detecting, and responding to biological threats, including diseases. The BAA emphasizes collaborative scientific studies to improve disease diagnostics, evaluate training programs, and establish biosecurity protocols, ultimately contributing to global biological threat reduction efforts. Interested applicants can find more information and submit proposals through the Grant Opportunities website, with the submission period running from April 29, 2024, to April 28, 2029. For inquiries, contact the CTR BAA Team at dtra.belvoir.ct.mbx.ctr-baa@mail.mil.
    Information Innovation Office (I2O) Office-Wide
    DARPA - Information Innovation Office
    The Defense Advanced Research Projects Agency (DARPA) is seeking proposals for revolutionary research ideas through its Information Innovation Office (I2O) under the Broad Agency Announcement (BAA) HR001126S0001. This opportunity invites innovative concepts that address topics not currently covered by ongoing I2O programs or other solicitations, with a focus on transformative advancements in areas such as AI, cybersecurity, and information systems. Proposals will be evaluated based on scientific merit, relevance to DARPA's mission, and cost realism, with a submission deadline for abstracts set for November 1, 2026, and a full proposal deadline of November 30, 2026. Interested parties can find more information and submit inquiries via the provided contact email: HR001126S0001@darpa.mil, and further details are available on SAM.gov.
    US Army Combat Capabilities Development Command Broad Agency Announcement
    ACC APG - Natick
    The U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center is inviting proposals through its Broad Agency Announcement (BAA) for scientific research and experimentation aimed at advancing state-of-the-art technologies. The BAA seeks innovative solutions in various areas, including combat feeding systems, soldier protection, human performance, and simulation technologies, without focusing on specific hardware solutions. This opportunity is crucial for enhancing military capabilities and overcoming existing technological barriers. Interested applicants, including universities, nonprofit research institutes, and commercial firms, must submit their proposals by February 27, 2030, with the potential for up to 1,500 awards. For further details, contact Lyndon Jagroop at 347-676-8382 or via email at lyndon.s.jagroop.civ@army.mil, and refer to the full announcement on SAM.gov.
    DEVCOM ANALYSIS CENTER BROAD AGENCY ANNOUNCEMENT FOR APPLIED RESEARCH
    Dept of the Army -- Materiel Command
    The Department of the Army's Materiel Command is inviting proposals through the DEVCOM Analysis Center's Broad Agency Announcement (BAA) for applied research funding, which is open until January 4, 2028. This opportunity seeks innovative research proposals that align with the Army's modernization and operational readiness objectives, emphasizing data-driven analytical decisions and collaboration with a diverse range of organizations, including educational institutions and private sector entities. The BAA aims to support cutting-edge research that can significantly impact Army technologies and operational capabilities, with no mandatory cost-sharing requirement for applicants. Interested parties should submit whitepapers for initial review and can contact the DEVCOM DAC BAA Email Inbox at DEVCOMDACBAA@army.mil for further information. Proposals will be evaluated based on scientific merit and potential contributions to the Army mission, with an expected 1,000 awards anticipated throughout the funding period.