DOD Amyotrophic Lateral Sclerosis, Therapeutic Idea Award
ID: 358726Type: Posted
Overview

Buyer

Dept. of the Army -- USAMRAA (DOD-AMRAA)

Eligible Applicants

Unrestricted

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/358726
Timeline
    Description

    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Therapeutic Idea Award (TIA) under the fiscal year 2025 Amyotrophic Lateral Sclerosis Research Program (ALSRP). This grant aims to support innovative, high-risk research proposals focused on drug or therapy development for Amyotrophic Lateral Sclerosis (ALS), with an emphasis on generating preliminary data for future therapeutic investigations. The program has a total funding amount of approximately $10.8 million, with individual awards capped at $600,000 and a performance period not exceeding two years. Interested applicants must submit pre-applications by June 6, 2025, and full applications by August 27, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.

    Point(s) of Contact
    help@eBRAP.org
    Files
    Title
    Posted
    A03.pdf
    The Department of Defense's (DoD) FY25 Amyotrophic Lateral Sclerosis Research Program announces the Therapeutic Idea Award (TIA), which seeks innovative and high-risk research proposals aimed at drug or therapy development for Amyotrophic Lateral Sclerosis (ALS). The program has a total funding amount of approximately $10.8 million, with a cap of $600,000 per application and a performance period not exceeding two years. Pre-applications are due by June 6, 2025, and full applications by August 27, 2025. Eligible applicants include both extramural and intramural organizations, with independent investigators serving as Principal Investigators regardless of their career stage. The award prioritizes innovative research that produces preliminary data for therapeutic applications, focusing on drug discovery rather than solely pathophysiological studies. The application process involves a two-step submission of a pre-proposal and full proposal, evaluated through peer and programmatic reviews based on criteria such as innovation, impact, and research strategy. Projects should also develop relevant biomarkers for ALS treatment outcomes. Successful applications will align with the DoD mission to improve health for military Service Members and Veterans affected by ALS, ensuring advancements are relevant to these populations.
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