The National Institutes of Health (NIH), through the National Institute on Alcohol Abuse and Alcoholism (NIAAA), is soliciting applications for a limited competition cooperative agreement under the funding opportunity titled "Collaborative Study on the Genetics of Alcoholism (COGA)." This initiative aims to explore the genetic variants affecting susceptibility to alcohol use disorder (AUD) to better understand its biological, behavioral, and environmental factors. With a budget of $6.5 million, the program invites proposals from existing COGA investigators to leverage extensive existing datasets involving thousands of participants. The research focuses on complex factors influencing AUD and aims to identify therapeutic targets and develop preventive strategies based on innovative data analysis approaches. Key activities include genetic data analysis, integration of multi-generational datasets, and public sharing of findings through NIH-designated repositories. The application process includes strict guidelines, eligibility requirements, and deadlines, with an emphasis on compliance and collaboration among diverse research teams. The goals of this research initiative are vital for advancing the understanding of AUD and informing public health strategies.