The National Institutes of Health (NIH) is inviting proposals for the "Innovative Research in Cancer Nanotechnology (IRCN; R01 Clinical Trial Not Allowed)" grant, aimed at fostering transformative discoveries in cancer biology through the application of nanotechnology. This initiative, led by the National Cancer Institute (NCI), seeks projects that address significant challenges in oncology by conducting mechanistic studies on nanomaterial interactions with biological systems, although clinical applications are not within the scope of this funding opportunity. The program emphasizes the importance of advancing cancer treatment and diagnostics through innovative research, with a funding ceiling of $475,000 per year for a maximum duration of five years. Interested applicants must submit their proposals by May 4, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries or visit the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-23-246.html for more details.