NASA Headquarters is soliciting information through a Request for Information (RFI) for Earth Independent Operations (EIO) Partnerships in Anomaly, aimed at developing technologies that enable human crews to operate independently of Earth-based support during critical missions. The RFI seeks capability statements from a diverse range of domestic organizations, including small businesses and Historically Black Colleges and Universities (HBCUs), to assess the availability of technologies that can address operational anomalies in space missions, particularly those related to life support, power, and communications. This initiative is crucial for ensuring crew safety and mission success during future Mars missions, where communication delays may hinder timely ground assistance. Interested parties must submit their responses electronically to Andres Martinez at NASA by January 26, 2026, with no solicitation currently available.