Pre-Clinical Consulting Services
ID: 75N95025Q00127_SBType: Sources Sought
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIDABethesda, MD, 20892, USA

NAICS

Other Scientific and Technical Consulting Services (541690)

PSC

SUPPORT- PROFESSIONAL: OTHER (R499)

Set Aside

Total Small Business Set-Aside (FAR 19.5) (SBA)
Timeline
  1. 1
    Posted Jan 15, 2025, 12:00 AM UTC
  2. 2
    Updated Jan 15, 2025, 12:00 AM UTC
  3. 3
    Due Jan 17, 2025, 2:00 PM UTC
Description

The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified small businesses to provide Pre-Clinical Consulting Services. The objective of this procurement is to gather information on the capabilities of potential contractors to support the Clinical Trials Unit (CTU) at the National Institute of Neurological Disorders and Stroke (NINDS), which oversees numerous clinical research programs and requires expertise in IND and IDE preparations. This initiative is crucial for enhancing clinical trial methodologies and improving research outcomes through strategic partnerships and expert guidance. Interested vendors must submit their capability statements electronically by January 17, 2025, to Frederick Weddington at frederick.weddington@nih.gov, ensuring compliance with specified formatting guidelines and confidentiality requirements.

Point(s) of Contact
Files
Title
Posted
Jan 15, 2025, 4:05 PM UTC
The file is a Sources Sought Notice (Solicitation Number: 75N95025Q00127_SB) issued by the federal government for Pre-Clinical Consulting Services. The notice seeks information on the availability and capabilities of small business sources, including those that are HUBZone, service-disabled, veteran-owned, woman-owned, and small disadvantaged businesses. The primary goal is to assess potential contractors' qualifications and domestic sourcing capabilities related to clinical research and gene therapy. Interested companies are required to submit detailed capability statements addressing each project requirement, including employee count and qualifications, along with their business type and NAICS code compliance. Responses can help determine acquisition methods, including possible set-asides for small businesses. The notice explicitly states it is for information gathering only and does not commit the government to any contract or payment, nor will responses be regarded as proposals. Responses must be submitted electronically by January 17, 2025, and must adhere to specified formatting guidelines. The notice also emphasizes the need for confidentiality regarding proprietary information. This Sources Sought Notice underscores the government's intention to identify qualified vendors for pre-clinical consulting services, promoting opportunities for small businesses in relevant sectors.
Jan 15, 2025, 4:05 PM UTC
The National Institutes of Health (NIH), through its National Institute of Neurological Disorders and Stroke (NINDS), is seeking consultancy services to support its Clinical Trials Unit (CTU). The CTU plays a pivotal role in overseeing over 120 clinical research programs, ensuring adherence to quality practices from protocol development through to data analysis. The need for external expertise arises due to the complexities involved in IND (Investigational New Drug) and IDE (Investigational Device Exemption) preparations, necessitating input from multiple stakeholders including the pharmaceutical industry, academia, and patient advocacy groups. Services will be provided virtually from the NINDS campus in Bethesda, MD, facilitating seamless collaboration using NINDS IT resources. The designated points of contact for this service order are Dr. Lauren Reoma and Mr. Bradley Alvarez. This initiative illustrates NINDS's commitment to enhancing clinical trial methodologies and improving research outcomes through strategic partnerships and expert guidance.
Lifecycle
Title
Type
Sources Sought
Similar Opportunities
NULISAseq CNS Disease Panel 120 Kit or Equivalent
Buyer not available
The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking information from qualified sources regarding the availability of the Alamar NULISAseq CNS Disease Panel 120 Kit or equivalent products. The objective is to procure three kits to aid in the investigation of biomarkers for neurodegenerative diseases, which are critical for early diagnosis and potential preventive measures. This procurement is essential for the NIH's Laboratory of Clinical Investigation, which focuses on isolating and measuring biomarkers from patient plasma to improve disease detection and management. Interested companies must submit their capability statements by April 11, 2025, to Eric McKay at eric.mckay@nih.gov, ensuring they include relevant details such as their business type and manufacturing information.
SOURCES SOUGHT: Signatures of aging outcomes
Buyer not available
The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified small business contractors to perform comprehensive immunohistochemistry analysis of 2,184 mice tissue samples as part of a project aimed at identifying age-associated phenotypic changes in various organs. The objective is to build proteomic signatures of aging outcomes through detailed histological analysis, which includes tasks such as tissue trimming, cassette preparation, paraffin embedding, sectioning, staining, and imaging. This initiative is crucial for advancing the understanding of aging and its effects on health, and the selected contractor will be required to provide progress reports and deliver electronic images and stained slides within one year of sample receipt. Interested parties must submit their capability statements to Rashiid Cummins at rashiid.cummins@nih.gov by April 4, 2025, at 9:00 am Eastern Time, adhering to specified formatting guidelines.
National Institute on Aging Animal Care Support Services
Buyer not available
The National Institute on Aging (NIA), part of the Department of Health and Human Services, is seeking qualified small businesses to provide comprehensive animal care support services for its Intramural Research Program (IRP) focused on aging and related diseases. The contractor will be responsible for a range of services including animal husbandry, veterinary support, technical research assistance, and ensuring compliance with strict animal welfare standards at the Biomedical Research Center (BRC) in Baltimore, Maryland. This opportunity is critical for maintaining the integrity of research data and the humane treatment of laboratory animals, reflecting the NIA's commitment to rigorous scientific standards. Interested parties must submit their capability statements by April 17, 2025, to Emily Palombo at emily.palombo@nih.gov and Karen Mahon at karen.mahon@nih.gov, with a focus on demonstrating their qualifications and compliance with the specified requirements.
Toxicity testing on a new PET ligand for the NIH
Buyer not available
The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking proposals for a toxicity testing service on a new PET ligand, Fluorine-18-Fluorocellobiose, as part of the requirements for an Investigational New Drug (IND) application to the FDA. The project entails conducting a single-dose toxicity study in Sprague Dawley rats to assess potential toxic effects, establish the maximum tolerated dose (MTD), and determine the no observable adverse effect level (NOAEL), all under Good Laboratory Practice (GLP) conditions. This initiative is crucial for advancing biomedical research and improving imaging techniques in the diagnosis and treatment of infectious diseases. Interested parties must submit their proposals by April 4, 2025, with the contract period expected to last for one year, and inquiries can be directed to Lu Chang at lu-chang.lu@nih.gov.
65--Cage & Rack Washer
Buyer not available
The Department of Health and Human Services, through the National Institutes of Health (NIH), is seeking information from small businesses regarding a procurement opportunity for a cage and rack washer to support laboratory animal care at the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK). This acquisition aims to replace an outdated system with a new, firm-fixed price model that integrates into existing infrastructure and includes operator training during startup. The cage and rack washer is vital for maintaining hygiene and health standards for laboratory rodents, which is essential for ensuring high-quality research outcomes. Interested small businesses are encouraged to submit a capability statement detailing their firm size, relevant experience, and references by April 9, 2025. For further inquiries, contact Airron Wiggins at airron.wiggins@nih.gov or call +1 410 504 9360.
75N93025R00013 - Medical Residents for NIH's Clinical Center
Buyer not available
The Department of Health and Human Services, through the National Institutes of Health (NIH), is soliciting proposals for the provision of Medical Residents at its Clinical Center in Bethesda, Maryland. The contract, structured as a Multiple Award Indefinite Quantity contract, aims to enhance clinical care for adult and pediatric inpatients involved in NIH research, requiring contractors to supply up to four postgraduate medical residents daily for a minimum of 80 hours per week. Proposals must be submitted by April 14, 2025, with a total funding range between $2,000 and $7,500,000 over the performance period from May 31, 2025, to May 30, 2030. Interested parties should direct inquiries to Sevag Kasparian or Maya Joseph via their provided emails for further clarification on the solicitation documents.
Extended Warranty and Technical Support for BBI-piPET-314-13
Buyer not available
The National Institutes of Health (NIH), specifically the National Institute on Drug Abuse (NIDA), is seeking to award a sole source contract to Brain Biosciences, Inc. for extended warranty and technical support services for the BBI-piPET-314-13 primate PET scanner. The primary objective of this procurement is to ensure the continued high-quality imaging performance of the scanner, which is vital for conducting research on substance use disorders (SUD). This contract will include annual preventative maintenance, software updates, diagnostic services, and emergency repairs, all aimed at supporting critical research initiatives. Interested parties may submit their capabilities and proposals to Shaun Rostad at shaun.rostad@nih.gov, with responses due by the specified deadline, as this opportunity is set aside for small businesses under NAICS code 811210.
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Seeks Industry Partners for Clinical Research Collaborations on Therapeutics, Diagnostics or Devices for the Liver Cirrhosis Network
Buyer not available
Special Notice HEALTH AND HUMAN SERVICES, DEPARTMENT OF seeks industry partners for clinical research collaborations on therapeutics, diagnostics or devices for the Liver Cirrhosis Network. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is looking for industry collaborators to provide novel or repurposed therapeutic agents, diagnostic markers, biomarkers, devices, or services for use in NIH-sponsored multi-center clinical trials and ancillary studies in adult patients with advanced liver disease and cirrhosis. The Liver Cirrhosis Network aims to promote clinical and translational research on cirrhosis of the liver and related complications in adults. The network is interested in conducting research that will lead to improved clinical outcomes in adults with cirrhosis and advanced liver disease. Commercial organizations interested in pursuing clinical collaborations with NIDDK for cirrhosis liver disease are required to submit a Capability Statement to the NIDDK.
Purchase of Lab Supplies
Buyer not available
The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified vendors to provide various lab supplies, including cleaning and sanitation products, under solicitation number 75N98025Q00021. The procurement aims to ensure the NIH is equipped with essential supplies such as paper towels, disinfectant wipes, and hand soap, which are critical for maintaining hygiene and safety in healthcare environments. This opportunity includes a partial small business set-aside, encouraging participation from small businesses, including service-disabled veteran-owned and women-owned enterprises, with a focus on timely delivery within a 10-day timeframe. Interested vendors must submit their quotes via email by 4:30 PM Eastern Daylight Time on April 9, 2025, and can direct inquiries to Carol Hayden at haydenc@od.nih.gov.
National Cancer Institute (NCI) Small Business Innovation Research (SBIR) Innovative Concept Award Program - Fiscal Year 2026
Buyer not available
The National Cancer Institute (NCI), part of the Department of Health and Human Services, is seeking proposals from small businesses for the SBIR Innovative Concept Award Program for Fiscal Year 2026. This program aims to support the development of innovative technologies for the treatment and prevention of pediatric and rare cancers, specifically targeting therapeutic technologies and diagnostic tools. The initiative is crucial for addressing cancers with low survival rates and encourages proposals that demonstrate technical feasibility and a clear development path, including initial proof-of-concept experiments. Interested small businesses must submit their proposals by September 26, 2025, with an interim white paper submission deadline in June 2025 for feedback. For further inquiries, contact Tanya Renwick at ncioasbir@mail.nih.gov.