The Defense Advanced Research Projects Agency (DARPA) is issuing a Special Topic Area (STA) for its "Expedited Research Implementation Series" to solicit innovative technological solutions that can enhance the U.S. industrial base. Open for submissions from May 1 to June 30, 2025, this effort includes a two-step submission process via the ERIS Marketplace, requiring a video pitch and supplementary materials. The initiative encompasses two primary objectives: conducting industrial base research to identify systemic constraints in manufacturing, capital formation, supply chains, and workforce; and designing stakeholder engagement events to gather actionable insights into scaling challenges. Proposals may focus on one or both areas, with expectations for structured outputs that integrate into ACO's broader modeling efforts. Further, organizations are expected to demonstrate rapid research and experimentation capabilities to generate timely, actionable insights. Evaluation criteria will assess the clarity of problem definition, advancements in state-of-the-art solutions, team capability, and potential impact on commercial and defense applications. The STA aims to address real-world constraints and foster collaboration across sectors to strengthen the U.S. industrial base.