Next Generation Sequencing System and Support Plan
ID: NIAID-SS-25-2265418Type: Combined Synopsis/Solicitation
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIDABethesda, MD, 20892, USA

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

PSC

LABORATORY EQUIPMENT AND SUPPLIES (6640)

Set Aside

No Set aside used (NONE)

Original Source

https://sam.gov/opp/b93100cec3f14e138b4a4a4caae97202/view
Timeline
    Description

    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotes for a Next Generation Sequencing System and Support Plan under solicitation number NIAID-SS-25-2265418. This procurement aims to acquire a NextSeq 2000 Sequencing System, which is essential for various clinical studies, including viral pathogenesis and the H5N1 Countermeasures Research Project, to enhance research capabilities in combating avian influenza. Interested vendors must submit their quotes by September 19, 2025, at 1:00 P.M. EST, including detailed pricing, shipping information, and compliance with specific technical requirements, with the anticipated period of performance for the support plan running from September 26, 2025, to September 25, 2026. For further inquiries, vendors can contact Shaun Rostad at shaun.rostad@nih.gov or Linda Smith at linda.smith2@nih.gov.

    Files
    Title
    Posted
    Attachment 4 - Statement of Needs.pdf
    The Statement of Need outlines the procurement of a Next Generation Sequencing System with specific technical requirements for a benchtop platform. The system must be compact (under 25in H x 23in W x 26in D, 325lbs) and offer diverse applications including single-cell, whole-exome, and RNA sequencing. Key capabilities include a minimum of 14 configurations, read lengths from 1x50bp to 2x300bp, 10-540Gb output, and 100M-1.8B single-end reads per run in 8-44 hours, utilizing patterned flow cell technology for maximum throughput and cost-efficiency. It must also feature advanced chemistry for faster, higher quality, and more economical sequencing. The workflow needs to be streamlined, requiring less than 10 minutes for setup, no wash cycle interruptions, cloud/on-premises sample tracking, and onboard data analysis under two hours. The system must integrate with 14 or more compatible library prep kits, supporting cloud/on-premises options and scalable sequence generation with exportable outputs. Crucially, the system must ensure seamless compatibility with existing Illumina instrumentation, platforms, and specifically with Illumina XLEAP-SBS™ reagent kits and Illumina Respiratory Virus kits to maintain continuity and accuracy of ongoing studies.
    CSS_NIAID-SS-25-2265418.pdf
    The National Institute of Allergy and Infectious Disease (NIAID) has issued a combined synopsis/solicitation (NIAID-SS-25-2265418) for a Next Generation Sequencing System and Support Plan. This Request for Quotation (RFQ) is for a brand name or equal product, specifically one NextSeq 2000 Sequencing System and a NextSeq 2000 Silver Support Plan. The system is crucial for clinical studies, viral pathogenesis, archaevirology, archaebacteriology, and the H5N1 Countermeasures Research Project. The procurement is a single-award, firm-fixed-price purchase order under Simplified Acquisition Procedures (FAR Part 13) and Acquisition of Commercial Items (FAR Part 12), with a NAICS code of 334516. Quotes are due by September 19, 2025, at 1:00 P.M. EST and must include pricing, shipping, country of origin, vendor authorization, delivery date, point of contact, UEI, CAGE code, business size, and payment terms. Evaluation will prioritize non-price factors like capability, salient characteristics, timely delivery, warranty, past performance, and reasonable price. The period of performance for the support plan is September 26, 2025, to September 25, 2026, with delivery of items within 90 days of order. The document also details invoicing instructions via the Invoice Processing Platform (IPP) and lists numerous applicable FAR and HHSAR provisions and clauses, including those related to ICT accessibility (Section 508).
    Lifecycle
    Title
    Type
    Next Generation Sequencing System and Support Plan
    Currently viewing
    Combined Synopsis/Solicitation
    Next Generation Sequencing System and Support Plan
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