The DARPA Advanced Research Concepts (ARC) Opportunity, titled "Hybridizing Biology and Robotics through Integration for Deployable Systems" (HyBRIDS), invites researchers to submit innovative proposals focused on biohybrid robotics for national security applications. The program encourages substantial, groundbreaking ideas that integrate synthetic and biological components to develop robotic systems that outperform traditional models. Proposals should aim to address significant challenges in creating biohybrid robots, including component integration, robust design methods, and deployment obstacles, with the expectation of a 12-month performance period and budgets ranging from $100,000 to $300,000. Researchers are required to justify the novelty and practicality of their proposed concepts, articulate the anticipated metrics, and describe the project’s schedule, while also considering ethical implications. The evaluation process will occur on a rolling basis until April 7, 2025, with no late submissions accepted. Selected proposals may lead to Research Other Transactions (OTs) agreements. This opportunity emphasizes the exploration of innovative pathways rather than incremental improvements, aiming to transform the field of biohybrid robotics for real-world applications and enhancing operational capabilities in complex environments.