Amendment 0001 to Solicitation 75N96025R00004, issued by the National Institutes of Health, extends the proposal due date to December 5, 2025, at 4:30 PM EST due to a government shutdown. A future amendment will provide answers to questions and may further extend the deadline. The period of performance is June 1, 2026, to May 31, 2027. The amendment clarifies that proposals must be submitted in separate Technical and Business parts. It also corrects the Point of Contact for Factor 6 Past Performance to Jason Williams (jason.williams2@nih.gov) and provides detailed instructions for submitting Past Performance Questionnaires (PPQs) or CPARS evaluations, emphasizing that CPARS are preferred. Offerors are responsible for providing detailed, current, accurate, and complete past performance information, with a recent and relevant project defined as a contract completed within the last five years with similar services.
RFP 75N96025R00004 Amendment 2 extends the proposal due date to December 19, 2025, at 4:30 PM EST, allowing offerors to review attached Questions and Answers and a revised Attachment 11 Budget Template. Key updates include a new Attachment 17 Technical Proposal Cost Summary, clarification on subcontractor labor hours, and the addition of the HHSAR 352.239-73 Electronic Information Technology Accessibility Notice. Proposals must comply with Section 508 standards, and offerors must provide a Section 508 Product Assessment Template. The amendment details requirements for business proposals, including itemized cost breakdowns and substantiation. Evaluation factors prioritize technical aspects, then past performance, and finally cost/price. The document also clarifies details on research plans, data management, meeting support, government-furnished property, and software licenses, with specific instructions for the revised budget template and subcontractor submissions. Travel costs for PIV card issuance will not be reimbursed.
This government file outlines a comprehensive cost and labor hour estimation framework for various research and administrative activities, including base and option years, and an optional 6-month extension. It details cost components such as direct labor, fringe benefits, overhead, general and administrative (G&A) expenses, and fees, along with other direct costs like materials/supplies and travel. The document provides instructions for populating yellow-highlighted cells with indirect rates, estimated hours, and labor rates, emphasizing the need for clear assumptions. Research outlines cover information and data extraction, computational tool development, interlaboratory studies (phases I and II), problem formulation, modeling, database and information support, and meeting support. Non-research activities include website maintenance and training support. The file also includes detailed breakdowns for meeting and participant travel, contractor travel, and professional meetings, distinguishing between international, domestic, and local events. The overall purpose is to provide a structured approach for calculating total estimated costs and labor hours across multiple projects and contract periods.
The National Institute of Environmental Health Sciences (NIEHS) seeks contractor support for evaluating and conducting computational and alternative toxicological methods. This non-personal service contract, RFP 75N96025R00004, focuses on developing and applying innovative tools to predict human-relevant health effects while reducing animal testing. Key areas include research and validation of computational and alternative toxicological approaches, meeting support, and communication management (website, database, training). The contractor must provide all necessary services, qualified personnel, and equipment, adhering to strict reporting, data management, and Section 508 compliance requirements. Deliverables include monthly and annual reports, research plans, and various research products like manuscripts and study reports. The contract emphasizes collaboration, data ownership by the government, and adherence to security and privacy policies.
The provided government file serves as a cost proposal template for various research outlines (ROs) and administrative support, including detailed breakdowns for direct labor, indirect costs (fringe, overhead, G&A, fee), and other direct costs such as subcontracts and materials/supplies. It outlines cost structures for a base year and nine option years, plus an optional 6-month extension. The document details specific research areas like "Information and data extraction - Mining ICE for chemical information," "Computational tool development," "Interlaboratory study phases I and II," "Problem formulation," "Modeling," "Database and Information Support," "Meeting Support - Workshop," "Website Maintenance," and "Training support." Additionally, it includes sections for contractor travel, meeting, and participant travel costs for various events such as expert group meetings, workshops, symposia, and professional meetings (local, domestic, and international). The template emphasizes filling in highlighted cells, avoiding formula changes unless necessary, and providing narrative and cost substantiation in a separate business proposal document. It is designed to capture both cost and labor hours for each activity and across all periods.
RFP 75N96025R00004, issued by the National Institute of Environmental Health Sciences (NIEHS) on September 17, 2025, seeks proposals from 100% small businesses to support the evaluation and conduct of computational and alternative toxicological methods. This acquisition aims to assist NIEHS in chemical hazard and risk assessment without animal testing, focusing on areas like population variability, developmental neurotoxicity, and carcinogenicity. Proposals are due by November 3, 2025, at 4:30 PM EST, and must be submitted electronically via the NIH eCPS website. The contract is a Cost-Plus-Fixed-Fee type, with a base period from June 1, 2026, to May 31, 2027, and nine one-year option periods, plus an option to extend services for up to six months. Key requirements include adherence to NIH policies on reproducibility, public access to research, and strict reporting for financial conflicts of interest and inventions. The contractor must also comply with federal records management and IT security standards.