The National Institutes of Health (NIH), specifically the National Institute of Allergy and Infectious Diseases (NIAID), intends to negotiate a sole-source annual service and maintenance agreement with Illumina, Inc. for the MiSeq and NextSeq 500 sequencing machines, which are critical for ongoing research operations. The contract will ensure the operational capability of these instruments from March 25, 2025, to March 24, 2030, including comprehensive service coverage such as parts, labor, software updates, and priority onsite support. This agreement is vital for maintaining the functionality of essential research equipment, thereby supporting NIAID's mission in viral pathogenesis and evolution studies. Interested vendors must submit their capability statements via the NIAID electronic Simplified Acquisition Submission System (eSASS) by March 17, 2025, at 10:00 AM EST, and should note that this notice does not constitute a request for proposals.