The Department of Defense, through the U.S. Army Medical Research Acquisition Activity (USAMRAA), intends to award a sole source contract to Aptagen, LLC for the generation of DNA Aptamer Libraries to support the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). The contract will require the generation of two DNA aptamer libraries annually, consisting of approximately 1,000 to 10,000 targeted aptamers aimed at specific alpha-conotoxins, palytoxins, and various viral targets, which are critical for the development of broad-spectrum DNA aptamers to neutralize toxins. Interested vendors may challenge this sole source determination by submitting a capability statement by 1300 Eastern Time on February 6, 2025, via email to the designated contacts, Christina Lewis and Jayme Fletcher, with no solicitation document currently available for this requirement.