PROTEOMIC ANALYSIS OF CANCER PATIENT PLASMA SAMPLES
ID: 75F40125Q00169Type: Combined Synopsis/Solicitation
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFFOOD AND DRUG ADMINISTRATIONFDA OFFICE OF ACQ GRANT SVCSBeltsville, MD, 20705, USA

NAICS

Research and Development in the Social Sciences and Humanities (541720)

PSC

SPECIAL STUDIES/ANALYSIS- SCIENTIFIC DATA (B529)

Original Source

https://sam.gov/opp/7b9573e6c4bf47ecb1dc9711fee3b204/view
Timeline
    Description

    The U.S. Department of Health and Human Services, specifically the Food and Drug Administration (FDA), is seeking a contractor to conduct a quantitative proteomic analysis of cancer patient plasma samples under solicitation number FDA-RFQ-75F40125Q00169. The objective is to analyze 100 human plasma samples for over 5000 proteins related to cardiotoxicity, cancer, and inflammation, with results delivered in organized parquet files within 60 days. This analysis is crucial for advancing research in cancer treatment and ensuring rigorous scientific evaluation of public health outcomes. Interested parties should contact Ronald Paraham at Ronald.Paraham@fda.hhs.gov for further details, with the contract being a firm-fixed price agreement and a performance period of 6 to 8 months.

    Point(s) of Contact
    Ronald Paraham
    Ronald.Paraham@fda.hhs.gov
    Files
    Title
    Posted
    FDA-RFQ-75F40125Q00169_LY.docx
    The U.S. Food and Drug Administration (FDA) issued a Request for Quote (RFQ) for quantitative proteomic analysis of cancer patient plasma samples under solicitation number FDA-RFQ-75F40125Q00169. This procurement aims to measure cardiotoxicity biomarkers using multiplex immunoassays, specifically targeting over 5000 proteins related to cardiovascular diseases, cancer, and inflammation. The contractor must deliver analysis results for 100 human plasma samples within 60 days, providing data in organized parquet files, and should ensure high sensitivity, specificity, and reproducibility of results with minimal sample volumes. Key requirements include using next-generation sequencing coupled with antibody-based assays, internal controls for data normalization, and the ability to assess bridging samples from prior analyses. The contract is a firm-fixed price agreement with a performance period of 6 to 8 months. The FDA retains ownership of all data produced. Invoices must be submitted electronically, and all work will occur at the contractor's facility, shipping results to the FDA’s National Center for Toxicological Research in Jefferson, AR. The RFQ is part of the FDA’s commitment to advancing research in cancer treatment, demonstrating a focus on rigorous scientific evaluation and public health outcomes.
    Lifecycle
    Title
    Type
    PROTEOMIC ANALYSIS OF CANCER PATIENT PLASMA SAMPLES
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    Combined Synopsis/Solicitation
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