EEG and dMRI data collection and analyses
ID: N32398-24-Q-3677Type: Combined Synopsis/Solicitation
Overview

Buyer

DEPT OF DEFENSEDEPT OF THE NAVYNAVAL MEDICAL RESEARCH CENTERSILVER SPRING, MD, 20910-7500, USA

NAICS

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) (541715)

PSC

SUPPORT- PROFESSIONAL: ENGINEERING/TECHNICAL (R425)
Timeline
    Description

    The Department of Defense, through the Naval Medical Research Center, is seeking proposals for a federal contract focused on EEG and dMRI data collection and analyses. The primary objective of this procurement is to support a study investigating the effects of acute hypoxia on neuroinflammation and signal transduction, utilizing a combined diffusion MRI and EEG approach to evaluate sensory information transfer and identify neuroinflammation biomarkers. This research is particularly significant for understanding cognitive and sensory impairments related to oxygen deprivation, which is critical for military aviation safety. Interested parties should contact Timothy A. Daniels at timothy.a.daniels18.civ@healty.mil for further details, with the project funded at $137,106 and expected to continue until September 30, 2026.

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    The document appears to focus on the digital signature of an individual named Timothy A. Daniels, dated September 10, 2024. While the specific details of any associated RFPs, federal grants, or state/local grants are not provided within the text, it emphasizes the use of electronic authentication in government processes. Digital signatures represent a key aspect of verifying identity and ensuring the integrity of documents in federal and local operations. This practice likely aligns with federal regulations aimed at streamlining workflows and enhancing security in government transactions. However, further context regarding specific RFPs or grants is not available from the limited content given in the file. Overall, the document reflects an ongoing trend towards digitization within government practices, promoting efficiency and accountability.
    The Naval Medical Research Unit – Dayton (NAMRU-D) is conducting a study titled "Investigating the Effects of Acute Hypoxia on Neuroinflammation and Signal Transduction" with funding of $137,106 from the Office of Naval Research's FY24 In-House Laboratory Independent Research (ILIR) program. The research, spanning until September 30, 2026, aims to explore the impact of acute hypoxia on neural transfer times and neuroinflammation using a combined diffusion MRI and EEG approach. The study's two main experiments focus first on evaluating interhemispheric transfer times of sensory information pre- and post-hypoxia, utilizing EEG and diffusion MRI. The second experiment seeks to identify in vivo neuroinflammation biomarkers via magnetic resonance spectroscopy, alongside assessing pro-inflammatory cytokines. For successful execution, the support team must establish MRI protocols and ensure participant safety, while NAMRU-D provides equipment, participants, and oversight. Deliverables include a project plan, status updates, and a final report summarizing findings. The initiative holds potential significance for understanding cognitive and sensory impairments due to oxygen deprivation, particularly in military aviation contexts, thereby contributing to safety-critical operational decisions.
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    Combined Synopsis/Solicitation
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