The Defense Health Agency (DHA) intends to modify an existing contract on a sole source basis with Aptagen, LLC for the provision of DNA aptamer library generation services to the United States Army Medical Research Institute of Infectious Diseases (USAMRIID). The contract modification aims to increase the service capacity, allowing for the generation of one to four DNA Aptamer Libraries per year, each consisting of approximately 1,000 to 10,000 targeted aptamers aimed at specific pseudoviruses and toxins. This initiative is critical for advancing USAMRIID's research capabilities in developing broad-spectrum DNA aptamers to neutralize toxins, a methodology that has not been previously employed at the institute. For further inquiries, interested parties can contact Christina Lewis at christina.m.lewis14.civ@health.mil or Jayme Fletcher at jayme.l.fletcher2.civ@health.mil.