Technology Transfer Licensing Opportunity: Diagnostic Kit to Detect Human Infertility
ID: TechnologyTransferLicensingOpportunity-DiagnosticKitToDetectHumanInfertilityType: Special Notice
Overview

Buyer

ENVIRONMENTAL PROTECTION AGENCYENVIRONMENTAL PROTECTION AGENCY

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

PSC

MISCELLANEOUS ITEMS (9999)

Original Source

https://sam.gov/opp/243d6af7c0d247bcb428178e9c4a3b2b/view
Timeline
    Description

    The U.S. Environmental Protection Agency (EPA) is offering a licensing opportunity for the development of a diagnostic kit designed to detect male infertility through the identification of the Sperm Membrane Protein 22 (SP22). This initiative aims to address the current ambiguity in male fertility indicators, as existing methods primarily rely on sperm motility and count, which can lead to inconsistent classifications of infertility among men. The patented technology, developed by inventor Gary R. Klinefelter and protected under U.S. Patent 8,497,135, has shown a strong correlation between SP22 and male fertility, with potential applications in human fertility testing, research, and comparative biology studies. Interested parties are encouraged to submit a license application form to the EPA’s Federal Technology Transfer Act team and can find more information on the licensing process at https://www.epa.gov/ftta. For inquiries, contact the team via email at ftta@epa.gov.

    Point(s) of Contact
    No information provided.
    Files
    Title
    Posted
    NCS Diagnostic Kit to Detect Infertility APR 2025.pdf
    The U.S. Environmental Protection Agency (EPA) is advancing a diagnostic kit aimed at detecting male infertility through the identification of the Sperm Membrane Protein 22 (SP22), a gene derived from Park 7. Inventor Gary R. Klinefelter has developed this patented kit (U.S. Patent: 8,497,135) to measure SP22 in motile semen samples, addressing the significant lack of consensus on male fertility indicators. Current markers rely heavily on sperm motility and count, leading to ambiguity in fertility categorization, as up to 20% of men may be deemed infertile under varying criteria. Recent laboratory research has reinforced the correlation of SP22 with male fertility and successful live births, facilitating the creation of a custom antibody for enhanced testing accuracy. The potential applications of this kit extend to human fertility testing, fertility research, and comparative biology studies. The EPA encourages collaboration and contact through Meghan Sheehan, an FTTA Specialist, to further develop this innovative tool for improving male infertility assessments in clinical settings.
    Similar Opportunities
    F--Superfund Analytical Methods Provisions & Clauses
    Buyer not available
    The Environmental Protection Agency (EPA) is seeking analytical services through the Superfund Analytical Methods (SFAM02.0) Solicitation to support its investigation and cleanup activities under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) and the Superfund Amendments and Reauthorization Act of 1986 (SARA). The procurement aims to provide essential analytical data that will assist the EPA in effectively managing environmental remediation efforts. This opportunity is critical for ensuring compliance with federal environmental regulations and facilitating the cleanup of contaminated sites. Interested parties can reach out to Mary K. Doherty at doherty.mary@epa.gov or (202) 564-8951 for further information regarding the solicitation and associated provisions.
    TECHNOLOGY LICENSING OPPORTUNITY: SmartBind pH Switch
    Buyer not available
    The Department of Energy is offering a technology licensing opportunity for the SmartBind pH Switch, an innovative advancement developed by scientists at Los Alamos National Laboratory. This technology significantly enhances the antibody purification process by utilizing a pH-switchable version of Protein G, allowing for gentle binding and release of antibodies without the damaging effects of harsh acidic conditions. The SmartBind pH Switch is particularly relevant for applications in biopharmaceuticals, life sciences research, and bioprocessing, providing improved stability, yield, and cost-effectiveness in antibody purification. Interested parties can reach out to Marc Witkowski or Lindsay Augustyn at licensing@lanl.gov for further discussions regarding licensing agreements, as this opportunity is not a call for external development services.
    TECHNOLOGY TRANSFER LICENSING OPPORTUNITY: Plasma Processing of Water and Inedible Biomass for pH Control and Nutrient Recycling (KSC-TOPS-94)
    Buyer not available
    NASA's Technology Transfer Program is offering a licensing opportunity for a novel technology developed at the Kennedy Space Center, which focuses on plasma processing of water and inedible biomass for pH control and nutrient recycling. This technology utilizes a plasma torch to generate plasma activated water and nutrient-rich ash from inedible biomass, allowing for adjustable pH levels suitable for plant growth and sanitation purposes. Interested companies can apply for exclusive or nonexclusive licensing rights through NASA’s Automated Technology Licensing Application System (ATLAS), with no funding provided by NASA for this opportunity. For inquiries, interested parties can contact NASA’s Technology Transfer Program via email at Agency-Patent-Licensing@mail.nasa.gov.
    B--Notice for EPA Laboratory ESAT Regions 04-05
    Buyer not available
    The Environmental Protection Agency (EPA) is preparing to issue a pre-solicitation notice for an Indefinite Delivery Indefinite Quantity (IDIQ) contract for laboratory services in EPA Regions 4 and 5. This contract will focus on testing laboratories and services, specifically in the area of chemical and biological special studies and analysis. The anticipated solicitation, expected to be released in December 2025 or January 2026, will be unrestricted with no set-aside, allowing for either a single award or multiple awards, with task orders issued non-competitively to the IDIQ awardees. For further inquiries, interested parties can contact Jeffrey Obirek at obirek.jeffrey@epa.gov or call 312-886-9092.
    TECHNOLOGY TRANSFER LICENSING OPPORTUNITY: Passive Porous Tube Nutrient Delivery System (KSC-TOPS-73)
    Buyer not available
    NASA's Technology Transfer Program is seeking inquiries from companies interested in obtaining licensing rights for the Passive Porous Tube Nutrient Delivery System (KSC-TOPS-73), a technology designed to enhance plant growth in microgravity environments. This innovative system addresses the challenges of delivering air, water, and nutrients to plant roots without the need for active pumping, which is currently required in existing methods used on the International Space Station. The licensing rights may be granted on either an exclusive or nonexclusive basis, and interested parties can submit their applications through NASA’s Automated Technology Licensing Application System (ATLAS) at the provided link. It is important to note that NASA does not provide funding in conjunction with these licenses, and no follow-on procurement is expected from this notice. For further inquiries, companies can contact NASA’s Technology Transfer Program via email at Agency-Patent-Licensing@mail.nasa.gov.
    TECHNOLOGY TRANSFER LICENSING OPPORTUNITY: Portable Microscope (MSC-TOPS-131)
    Buyer not available
    NASA's National Aeronautics and Space Administration is offering a licensing opportunity for a portable digital microscope developed by innovators at the Johnson Space Center. This technology is designed to support human space exploration by providing flight crews with in situ hematological diagnostic capabilities, enabling health monitoring in microgravity environments. The microscope, which is currently utilized aboard the International Space Station, is self-contained, durable, and capable of high-resolution imaging, making it suitable for various applications on Earth as well. Interested companies can submit a license application through NASA’s Automated Technology Licensing Application System (ATLAS) and should direct any inquiries to NASA’s Technology Transfer Program at Agency-Patent-Licensing@mail.nasa.gov. Please note that NASA does not provide funding for this licensing opportunity, and no follow-on procurement is expected.
    66--TEST KIT, HP
    Buyer not available
    The Department of Defense, specifically the Department of the Navy, is seeking proposals for the manufacture of three units of a Test Kit HP, identified by NSN 7H-6685-017081470-X5. The procurement requires delivery of these kits to designated distribution centers in Pennsylvania and California within 140 days after contract award, emphasizing the importance of timely fulfillment for operational readiness. This opportunity is set aside for small businesses under the Total Small Business Set-Aside program, and interested parties must contact Michael B. Duffy at 564-230-2254 or via email at MICHAEL.B.DUFFY2@NAVY.MIL to obtain the solicitation number N00104-26-Q-BE38 and further details. Proposals must adhere to the requirements outlined in the solicitation, and government source inspection will be required.
    TECHNOLOGY LICENSING OPPORTUNITY: Remotely Operated Ultrasonic Separation (UltraSep)
    Buyer not available
    The Department of Energy is offering a technology licensing opportunity for UltraSep, a novel ultrasonic separation technology developed by Los Alamos National Laboratory. This technology aims to address inefficiencies in traditional filtration methods used in industrial manufacturing by providing a membrane-free solution that significantly reduces maintenance disruptions and operational footprint. UltraSep is designed for applications in various sectors, including food and beverage production, pharmaceutical processes, and critical nuclear operations, achieving over 99.9% metal removal and up to 95% bulk water extraction. Interested parties can reach out to Marc Witkowski or Lindsay Augustyn at licensing@lanl.gov for further discussions regarding partnership opportunities, as the technology is currently at Technology Readiness Level 5 and available for licensing agreements.
    R--EPA Environmental Services Assistance Team (ESAT)
    Buyer not available
    The Environmental Protection Agency (EPA) is seeking proposals for the Environmental Services Assistance Team (ESAT) to support Regions 1, 2, 3, 8, 9, and 10. This procurement aims to provide essential environmental services, which may include testing and laboratory services, to enhance the EPA's operational capabilities in these regions. The services are critical for ensuring compliance with environmental regulations and supporting various environmental initiatives. Interested parties should note that questions regarding the Request for Proposal (RFP) will be addressed by December 8, 2025, with the RFP submission deadline extended to December 30, 2025, at 5 PM PT. For further inquiries, contact Emily Mogg at Mogg.Emily@epa.gov or call 415-972-3711.
    F--EPA WATER RFP
    Buyer not available
    The Environmental Protection Agency (EPA) is soliciting proposals for its Water Assessment and Technical Emergency Response (WATER) Contract through a Request for Proposal (RFP). This procurement aims to engage qualified contractors to provide environmental consulting services, specifically focusing on water-related assessments and emergency response initiatives. The services sought are critical for ensuring effective management and response to water quality issues, which play a vital role in public health and environmental protection. Interested parties can reach out to Emily Mogg at Mogg.Emily@epa.gov or by phone at 415-972-3711 for further details regarding the solicitation and any associated deadlines.