AN12--Research Laboratory Services for DNA Testing Reducing Veterans Risk of Atherosclerotic Cardiovascular Disease Through Pharmacogenomics Informed Statin Prescribing
ID: 36C24E25Q0023Type: Sources Sought
Overview

Buyer

VETERANS AFFAIRS, DEPARTMENT OFVETERANS AFFAIRS, DEPARTMENT OFRPO EAST (36C24E)PITTSBURGH, PA, 15212, USA

NAICS

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) (541715)

PSC

HEALTH R&D SERVICES; HEALTH CARE SERVICES; APPLIED RESEARCH (AN12)

Original Source

https://sam.gov/opp/fcf90ddd41f6406e93fe55264d07ef80/view
Timeline
    Description

    The Department of Veterans Affairs is seeking qualified contractors to provide research laboratory services for DNA testing aimed at reducing veterans' risk of atherosclerotic cardiovascular disease through pharmacogenomics-informed statin prescribing. The project involves supporting the Health Science Research Department at the Durham VA Medical Center by conducting a randomized clinical trial with 410 veteran patients, comparing outcomes of genetic testing against standard care. This initiative is critical for enhancing clinical decision-making through advanced genetic testing services, including DNA sequencing and polygenic risk score calculations. Interested vendors must submit their capability statements by January 6, 2025, to Karly Gabrysiak at karly.gabrysiak@va.gov, as the anticipated contract duration is from January 13, 2025, to January 12, 2026, with options for yearly renewals.

    Point(s) of Contact
    Karly GabrysiakContract Specialist
    E-Mail only
    karly.gabrysiak@va.gov
    Files
    Title
    Posted
    36C24E25Q0023.docx
    The Federal Government is seeking sources for a contract focused on providing research laboratory services for DNA testing to reduce veterans' risk of atherosclerotic cardiovascular disease through pharmacogenomics-informed statin prescribing. This notice invites qualified businesses to respond, as it aids in determining the best acquisition method by gathering information on market capabilities. The contractor will support the Durham VA Medical Center's Health Science Research Department and perform genetic testing in line with strict clinical guidelines while respecting privacy and security requirements. The project encompasses a randomized clinical trial involving 410 veteran patients, comparing genetic testing outcomes versus standard care. Key services include DNA sequencing, polygenic risk score calculations, and reporting to enhance clinical decision-making. The anticipated contract duration is from January 13, 2025, to January 12, 2026, with possible yearly renewals. Interested vendors are encouraged to submit detailed capability statements by the specified deadline, allowing the government to evaluate potential sources for meeting this crucial health initiative for veterans. Responses should be submitted via email and should showcase the vendors’ experience and ability to meet specified requirements within the context of federal contracting.
    Similar Opportunities
    VISN 1 Primary Reference Laboratory Testing
    Active
    Veterans Affairs, Department Of
    The Department of Veterans Affairs is seeking qualified contractors to provide reference laboratory testing, phlebotomy, and courier services for all VISN 1 sites, primarily located in Manchester, New Hampshire. The procurement aims to ensure comprehensive laboratory services, including specimen collection, transportation, and testing, in compliance with federal regulations and quality assurance standards. This initiative is crucial for enhancing healthcare delivery to veterans, ensuring timely and accurate diagnostic services across multiple states. Interested parties must submit their responses by January 3, 2025, to Cynthia Thompson at Cynthia.Thompson2@va.gov, including relevant company information and past contract details.
    Genotyping Services
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is seeking proposals for genotyping services to analyze 1,500 DNA samples related to Alzheimer's Disease and Related Dementias research. The selected contractor will perform microarray genotyping using Illumina Infinium Global Diversity + Neurobooster Arrays, ensuring quality control and timely reporting of results to support the National Institute on Aging's objectives in advancing research in this critical area. Proposals must be submitted electronically by 11:00 A.M. Eastern on December 27, 2024, to Hashim Dasti at hashim.dasti@nih.gov, with the anticipated award being a firm fixed-price purchase order for a period of twelve months after receipt of order. Interested parties should ensure compliance with all applicable federal regulations and provide evidence of their capability to fulfill the requirements outlined in the solicitation.
    Q301--Lab Testing Services - (USP 797 Gloved fingertip test/Off) - Philadelphia
    Active
    Veterans Affairs, Department Of
    The Department of Veterans Affairs is seeking proposals for lab testing services, specifically the USP 797 Gloved Fingertip Test, at the Corporal Michael J. Crescenz VAMC in Philadelphia, PA. The procurement aims to award a single five-year Fixed Price Indefinite Delivery/Indefinite Quantity (IDIQ) contract, commencing on January 15, 2025, to ensure compliance with environmental microbiology testing standards critical for patient safety and pharmacy operations. This contract is set aside for Service-Disabled Veteran-Owned Small Businesses (SDVOSB) and requires registration with the System for Award Management (SAM) prior to award. Interested parties must submit their quotations by January 2, 2025, and can contact Contract Specialist Kevin Lake at Kevin.Lake1@va.gov for further information.
    6630--V16 Lab Chemistry and Immunochemistry CPRR BPA (VA-25-00010416)
    Active
    Veterans Affairs, Department Of
    The Department of Veterans Affairs (VA) is preparing to issue a Request for Quotation (RFQ) for a Blanket Purchase Agreement (BPA) focused on Chemistry and Immunochemistry instrumentation and testing for the South Central VA Health Care Network (VISN 16). This procurement aims to standardize automated equipment across 8 medical center and 20 outpatient laboratories, ensuring compliance with the 1988 Clinical Laboratory Improvement Act and FDA approval for all reagents, while also providing operator training and 24/7 repair services. The initiative underscores the VA's commitment to enhancing laboratory capabilities through modern technology, with site visits permitted until February 28, 2025, allowing vendors to assess laboratory conditions and align their offerings with specific site requirements. Interested contractors can contact Diyonne Williams, the Contracting Officer, at Diyonne.Williams@va.gov for further information.
    Q301--Gloved Fingertip and Thumb (GFT) Media, Direct Compounding Area (DCA) Media and Media Fill Test Services (VANCHCS)
    Active
    Veterans Affairs, Department Of
    The Department of Veterans Affairs (VA) is seeking qualified contractors to provide Gloved Fingertip and Thumb (GFT) media, Direct Compounding Area (DCA) media, and media fill test services for the VA Northern California Health Care System (VANCHCS). The procurement involves laboratory services for microbial testing, including the incubation and analysis of GFT samples, Media-fill Test (MFT) samples, and various viable air and surface samples, adhering to the 2023 USP standards. This contract, valued at approximately $19 million, spans a base performance period from March 1, 2025, to February 28, 2026, with potential extensions for up to five years, and is set aside for small businesses, particularly those owned by veterans. Interested parties must submit their proposals by December 31, 2024, at 1:00 PM Pacific Time, and can contact Contract Specialist Durell M Salaz at durell.salaz@va.gov for further information.
    Automated Glycohemoglobin Instrumentation
    Active
    Veterans Affairs, Department Of
    The Department of Veterans Affairs (VA) is seeking a contractor to establish an Indefinite Delivery Indefinite Quantity (IDIQ) contract for Automated Glycohemoglobin Instrumentation across its facilities within Veterans Integrated Service Network (VISN) 4. The procurement aims to provide essential equipment, reagents, and services for Hemoglobin A1C testing, which is crucial for diabetes management among veterans. This contract will cover a base year with four optional renewal periods, extending from April 1, 2025, to March 31, 2030, and emphasizes compliance with regulatory standards, continuous support, and effective inventory management. Interested vendors should contact Debra Willard at debra.willard@va.gov, with proposals due by January 15, 2025, under solicitation number 36C24425Q0165.
    The Role of Mitochondrial Genetic Variation in Dementia
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified small business sources for a project titled "The Role of Mitochondrial Genetic Variation in Dementia." The objective of this procurement is to obtain laboratory analysis of mitochondrial genetic variation in brain tissue samples from dementia patients, which will aid in understanding the relationship between mitochondrial function and Alzheimer's disease. This initiative is crucial as it aims to explore potential pathways to dementia through the examination of mitochondrial DNA mutations and oxidative capacity in patient samples. Interested contractors must submit their responses by January 2, 2025, to Kevin Alvarez at kevin.alvarez@nih.gov, detailing their capabilities and business size status, as this opportunity is particularly focused on small businesses.
    6640--VISN Blanket Purchase Agreement NEW Coagulation CPRR
    Active
    Veterans Affairs, Department Of
    The Department of Veterans Affairs (VA) is seeking proposals for a Blanket Purchase Agreement (BPA) to acquire coagulation analyzers, related equipment, reagents, and services for various VA medical facilities. The procurement aims to ensure the availability of high-quality coagulation testing capabilities, which are critical for patient diagnosis and treatment, over a five-year term from February 1, 2025, to January 31, 2030. This opportunity emphasizes compliance with federal guidelines, including cybersecurity measures for medical devices, and prioritizes service-disabled veteran-owned businesses. Interested vendors must submit their proposals by January 6, 2025, and can contact Contracting Specialist Lindsey M Zwaagstra at Lindsey.Zwaagstra@va.gov for further information.
    Molecular HIV-PCR Test Equipment Maintenance
    Active
    Veterans Affairs, Department Of
    The Department of Veterans Affairs intends to award a sole source contract for the maintenance of Molecular HIV-PCR Test Equipment, specifically targeting Roche Diagnostics Corp. This procurement involves the provision of microbiology molecular diagnostics reagents and analyzer rental, including the Roche 6800 and Cobas Prime pre-analytical instruments, along with maintenance and emergency services for the equipment. The contract is crucial for supporting analytical services related to various infectious diseases, including HIV and COVID-19, and is expected to be finalized by February 2, 2025. Interested parties must submit evidence of capability by December 26, 2024, to Alecia Mitchell at alecia.mitchell@va.gov, as the government retains discretion on whether to compete the procurement.
    A--National Gene Vector Biorepository
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is seeking proposals for the National Gene Vector Biorepository (NGVB) to support gene therapy research for the National Heart, Lung, and Blood Institute (NHLBI). The contract aims to provide essential resources and services, including administrative management, core laboratory activities, and compliance with FDA regulations and Good Laboratory Practices (GLP). This initiative is crucial for advancing gene therapy capabilities and ensuring the proper archiving of biological specimens and development of assays. Proposals must be submitted by January 10, 2025, and should include detailed technical and business plans, with specific formatting guidelines and a budget submission required. For further inquiries, interested parties can contact Ethan J. Mueller at ethan.mueller@nih.gov or +1 301 496 2153.