Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences
ID: NICEATM_RFI-SS_NIEHS_2023Type: Sources Sought
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTE OF HEALTH NIEHSMORRISVILLE, NC, 27560, USA

NAICS

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) (541715)

Original Source

https://sam.gov/opp/770fe90028a1491e8f0a6c459b7e9fa2/view
Timeline
    Description

    The Department of Health and Human Services, through the National Institute of Health's National Institute of Environmental Health Sciences (NIEHS), is seeking small businesses to provide support for evaluating and conducting computational and alternative toxicological methods. The primary objective of this procurement is to enhance human health hazard assessments while minimizing the use of animal testing, focusing on innovative methodologies such as computational toxicology and in vitro approaches. This initiative is crucial for advancing toxicological science and improving testing practices, reflecting the federal government's commitment to public health and environmental safety. Interested parties must submit their responses by November 29, 2024, and can direct inquiries to Megan Bang at megan.bang@nih.gov or Erica Kitzmiller at erica.kitzmiller@nih.gov.

    Point(s) of Contact
    Megan Bang
    megan.bang@nih.gov
    Erica Kitzmiller
    erica.kitzmiller@nih.gov
    Files
    Title
    Posted
    Draft SOW - NAM.pdf
    The Statement of Work (SOW) outlines the requirements for a contract providing support for evaluating computational and alternative toxicological methods for the National Institute of Environmental Health Sciences (NIEHS). The primary purpose is to assist in research using new approach methodologies (NAMs) to improve human health hazard assessments while reducing reliance on animal testing. Services include scientific and administrative support in areas such as research development, validation of alternative test methods, communication management, and meeting support. The contractor's responsibilities encompass developing computational toxicology approaches, conducting validation studies, and managing databases related to toxicology methods. Compliance with established guidelines from the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and the Organisation for Economic Co-operation and Development (OECD) is imperative. Comprehensive reporting, including monthly status updates and annual reports, is required to ensure accountability and transparency. Key areas of focus include training, public communication, and the promotion of innovative methodologies to foster confidence in human-relevant health testing strategies. This contract reflects the federal government’s commitment to advancing toxicological science while safeguarding public health and environmental safety through improved testing practices.
    NICEATM_DRAFT-SOW_NIEHS_2023.pdf
    NICEATM_RFI-SS_NIEHS_2023.pdf
    SB Sources Sought Notice.pdf
    The NIH's National Institute of Environmental Health Sciences (NIEHS) issued a Small Business Sources Sought Notice (SSN) to solicit information from capable small businesses for scientific and administrative support in developing alternative toxicological methods. The goal is to improve human health predictions while minimizing animal use in toxicity testing, emphasizing innovative methodologies like computational toxicology and in vitro approaches. The anticipated contract, estimated at ten years with 30,000 to 60,000 labor hours annually, is intended to support the NIEHS’s Division of Translational Toxicology (DTT) initiatives and assist the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). Responses are sought to gauge the market and capabilities available, with detailed company information and examples of relevant experience required. The deadline for questions is November 22, 2024, with submissions due by November 29, 2024. This request reflects the government's effort to engage small businesses in advancing scientific research methodologies for toxicology.
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