SOURCES SOUGHT: Automated Cell Dissociation Apparatus
ID: 75N95025Q00116Type: Sources Sought
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIDABethesda, MD, 20892, USA

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

PSC

LABORATORY EQUIPMENT AND SUPPLIES (6640)
Timeline
    Description

    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking to procure an Automated Cell Dissociation Apparatus to enhance research capabilities in neurodegenerative diseases. The apparatus, specifically the S2 Genomics Singulator 100 Cell Dissociation Platform, is required to facilitate the isolation of single nuclei from human and mouse brain tissues, supporting various cell types while ensuring fast and reproducible tissue dissociation. This procurement is critical for advancing scientific research in areas such as ALS, Parkinson's, and Alzheimer's diseases. Interested vendors should contact Rashiid Cummins at rashiid.cummins@nih.gov, with delivery expected within 60 days post-award.

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    This document outlines the mandatory Federal Acquisition Regulation (FAR) clauses incorporated into a government contract, ensuring compliance with applicable laws and Executive orders related to the acquisition of commercial products and services. Key clauses include stipulations on subcontractor sales restrictions, contractor business ethics, whistleblower protections, and various small business considerations, such as set-asides and subcontracting plans. Notable regulations also address prohibitions against contractors using certain telecommunications services and mandates for veteran and disability employment opportunities. Additionally, the document specifies requirements for transparency in contractor reporting and the promotion of sustainability in procurement practices. By enforcing these regulations, the contract aims to uphold integrity, encourage small business participation, and ensure fair labor practices within government procurement processes.
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    The document outlines a clause regarding Information and Communication Technology (ICT) Accessibility, emphasizing compliance with Section 508 of the Rehabilitation Act. It mandates that all ICT products and services developed, acquired, or delivered under the contract must meet the Revised 508 Standards for accessibility. Contractors are tasked with ensuring that their ICT offerings conform, and any non-compliance requires them to handle remediation at their own cost. For contract modifications or task orders involving new ICT, contractors must submit accessibility checklists or conformance reports to verify compliance. Additionally, contractors must disclose any exceptions to the Section 508 requirements, ensuring transparency in their obligations for accessibility. This clause is significant within the context of government RFPs and grants, reinforcing the federal commitment to making technology accessible for individuals with disabilities.
    The National Institute on Aging (NIA) seeks to procure an automated cell dissociation apparatus to facilitate single nuclei isolation from human and mouse brain tissues, aiding in research on neurodegenerative diseases such as ALS, Parkinson's, and Alzheimer's. The chosen product is the S2 Genomics Singulator 100 Cell Dissociation Platform, which must fit on a bench-top, utilize single-use cartridges, and enable fast, reproducible tissue dissociation into cell or nuclei suspensions. It should support various cell types from multiple tissue sources and avoid lengthy centrifugation processes. Additionally, the platform's software must allow customization of processing parameters, such as mincing and enzyme incubation conditions. The delivery is expected within 60 days post-award. This request underscores the NIA's commitment to advancing scientific research through innovative laboratory technology.
    The National Institute on Aging (NIA), Laboratory of Neurogenetics (LNG) seeks an automated cell dissociation apparatus specifically for isolating single nuclei from human and mouse brain tissues. This acquisition aims to advance research on neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease, and Alzheimer's disease, facilitating future single-cell sequencing studies. The preferred model is the S2 Genomics Singulator 100 Cell Dissociation Platform, which must meet several specific requirements, including bench-top compatibility, single-use cartridges, and the ability to produce rapid and reproducible single-cell or nuclei suspensions from various tissue sources. The apparatus should employ pre-set protocols for cell nuclei isolation and feature customizable software to adjust parameters like enzyme incubation times and mechanical disruption methods. The delivery of this equipment is expected within 60 days following the award. The request underscores the NIA's commitment to furthering scientific understanding of neurodegenerative diseases through advanced technological tools.
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