SOURCES SOUGHT: Automated Cell Dissociation Apparatus
ID: 75N95025Q00116Type: Sources Sought
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIDABethesda, MD, 20892, USA

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

PSC

LABORATORY EQUIPMENT AND SUPPLIES (6640)
Timeline
    Description

    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified small businesses to provide an automated cell dissociation apparatus for the National Institute on Aging's Laboratory of Neurogenetics. The primary objective of this procurement is to acquire equipment capable of isolating single nuclei from human and mouse brain tissues, which is crucial for advancing research on neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease, and Alzheimer's disease. The preferred model for this apparatus is the S2 Genomics Singulator 100 Cell Dissociation Platform, which must meet specific requirements including bench-top compatibility, single-use cartridges, and customizable software for protocol adjustments. Interested companies must submit their capability statements by January 17, 2025, to Rashiid Cummins at rashiid.cummins@nih.gov, ensuring they include all necessary documentation and adhere to the specified format.

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    Title
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    The National Institute on Aging (NIA), Laboratory of Neurogenetics (LNG) seeks an automated cell dissociation apparatus specifically for isolating single nuclei from human and mouse brain tissues. This acquisition aims to advance research on neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease, and Alzheimer's disease, facilitating future single-cell sequencing studies. The preferred model is the S2 Genomics Singulator 100 Cell Dissociation Platform, which must meet several specific requirements, including bench-top compatibility, single-use cartridges, and the ability to produce rapid and reproducible single-cell or nuclei suspensions from various tissue sources. The apparatus should employ pre-set protocols for cell nuclei isolation and feature customizable software to adjust parameters like enzyme incubation times and mechanical disruption methods. The delivery of this equipment is expected within 60 days following the award. The request underscores the NIA's commitment to furthering scientific understanding of neurodegenerative diseases through advanced technological tools.
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