Brand name or equal, Reagent needed for amplification of DNA for next generation sequencing in high-throughput assay for chromatin for The National Center for Advancing Translational Sciences (NCATS)
ID: 75N95025Q00122Type: Sources Sought
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIDABethesda, MD, 20892, USA

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

PSC

LABORATORY EQUIPMENT AND SUPPLIES (6640)
Timeline
    Description

    The National Institutes of Health (NIH) is seeking suppliers for a brand name or equal reagent necessary for the amplification of DNA for next-generation sequencing in high-throughput assays for chromatin, specifically for the National Center for Advancing Translational Sciences (NCATS). The procurement aims to acquire the NEBNext Ultra II Q5 Master Mix in a bulk order of 500 mL, which is critical for optimizing protocols and facilitating high-throughput screening. This reagent is essential for advancing medical research and enhancing the development of diagnostics and therapeutics across various human diseases. Interested vendors must submit their capability statements and relevant documentation by January 22, 2025, at 9 am Eastern Time to Giuliana Faller at giuliana.faller@nih.gov.

    Point(s) of Contact
    Files
    No associated files provided.
    Similar Opportunities
    NUcleic acid Linked Immuno-Sandwich Assay Reagents
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking proposals for the procurement of NUcleic acid Linked Immuno-Sandwich Assay Reagents, aimed at enhancing biomarker discovery for neurodegenerative disease research at the Center for Alzheimer’s Disease and Related Dementias (CARD). The acquisition includes the Alamar NULISAseq Inflammation Panel, with a requirement for 30 units that must demonstrate high sensitivity in analyzing over 250 proteins from minimal sample volumes, ensuring compatibility with the ARGO proteomics platform. This procurement is critical for advancing research capabilities in the detection of biomarkers related to Alzheimer’s Disease and Related Dementias (ADRD). Interested vendors must submit their quotations by January 22, 2025, at 12:00 PM Eastern Time, to Andrea Clay at amcgee@nida.nih.gov, and must comply with all specified federal regulations and provisions outlined in the solicitation.
    SOURCES SOUGHT: Mass Spectrometry Reagents
    Active
    Health And Human Services, Department Of
    The National Institutes of Health (NIH), specifically the National Institute on Aging (NIA), is seeking qualified small business sources for the procurement of specialized Mass Spectrometry Reagents aimed at advancing research on Alzheimer’s Disease and related dementias. The objective is to establish a national resource of isogenic induced pluripotent stem cell (iPSC) lines to study genetic mutations associated with these diseases, thereby accelerating mechanistic discovery. This procurement is critical for enhancing the understanding of Alzheimer’s disease mechanisms and includes specific requirements for HPLC columns and related supplies, with the first delivery expected by July 7, 2025, and additional options extending to July 2027. Interested parties should submit their capability statements to Rashiid Cummins at Rashiid.Cummins@nih.gov by January 21, 2025, at 3:00 PM Eastern Time.
    Notice of Intent BD Rhapsody Single-Cell Analysis Reagent Kits
    Active
    Health And Human Services, Department Of
    Notice of Intent BD Rhapsody Single-Cell Analysis Reagent Kits The Department of Health and Human Services, Department of, National Institutes of Health, is planning to procure BD Rhapsody Single-Cell Analysis Reagent Kits. These kits are used for the manufacture of human cells and tissue-based products utilized in phase I/II clinical protocols for transplantation, adoptive immunotherapy, and gene therapy conducted in the Clinical Center at the NIH. The procurement includes a standing order for multi-type sequencing kits and reagents with a short shelf life. The contractor will be responsible for shipping the sufficient reagents and kits following the scheduled delivery dates. The shelf life of the sequencing reagents should be at least 3 months, and the shelf life of library generation kits should be at least 6 months. The contractor is also required to provide technical support for all kits and reagents at no additional cost. The period of performance for this procurement is from 5/1/2024 to 8/30/2024. The delivery schedule is overnight delivery Monday through Thursday to the Center for Cellular Engineering (CCE) at NIH/CC in Bethesda, MD. The vendor will be responsible for ensuring the safe transport of cryopreserved patient cells and maintaining the temperature and other parameters during the shipment of reagents and kits. The contractor will be paid per product delivered and is required to provide hard copies of proofs of each product delivered. Interested parties can submit their capabilities to the Office of Purchasing and Contracts by May 1st, 9:00 AM EST. Please note that this is not a request for proposal.
    Assay Kits for Lumipulse instrument
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking proposals for the procurement of assay kits for the Lumipulse instrument, aimed at quantifying specific biomarkers related to Alzheimer's Disease. The acquisition includes a total of 4,410 assays for measuring abeta42, abeta40, and pTau 217, which will support ongoing research into cognitive decline and neurodegeneration using samples from the Baltimore Longitudinal Study of Aging. Interested vendors must submit their quotations by 5:00 p.m. Eastern Time on January 15, 2025, and can direct inquiries to Iris Merscher at iris.merscher@nih.gov or by phone at 301-827-2547. This procurement is conducted under simplified acquisition procedures and is open to all qualified offerors without set-aside restrictions.
    Chemistry Analyzer Piccolo Xpress, CLIA Waived (AMBIS 2247161)
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotes for the procurement of two Piccolo Xpress Chemistry Analyzers, essential for ongoing clinical trials in Kenya. The analyzers must be brand-name Piccolo Xpress models to ensure compatibility and continuity with existing laboratory equipment, as they are critical for accurate and reliable diagnostic testing in the Vaccine Research Center's post-discharge study. This procurement reflects the NIH's commitment to enhancing clinical diagnostics capabilities through efficient and portable testing solutions. Interested vendors must submit their quotes by January 13, 2025, at 4:00 PM EST, and can direct inquiries to Rita Davis at rita.davis@nih.gov or Tonia Alexander at talexander@niaid.nih.gov.
    Acquisition of SomaScan 7K and 11K Assay Kits
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking to procure fifty-nine (59) SomaScan 7K and/or 11K Assay Kits on a sole source basis from SomaLogic Operating Co., Inc. This acquisition is intended to support the Center for Human Immunology, Inflammation, and Autoimmunity (CHI) in their systems biology research, which involves measuring a wide range of proteins in various human biological samples to enhance understanding of the immune system and related diseases. The procurement aligns with federal initiatives to advance health science research capabilities, with an estimated delivery date for the products set for December 20, 2024, and a performance period from February 21, 2025, to February 20, 2026. Interested vendors may contact Kathy Song at kathy.song@nih.gov for further information and must submit their capabilities statements within 15 days of this notice.
    Maintenance service for Mass Spectrometers and components
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified small businesses to provide maintenance services for Mass Spectrometers and associated components utilized by the National Institute on Aging (NIA). The procurement aims to ensure the proper functioning of critical instruments, including the Q Exactive HF and Orbitrap Eclipse Tribid, which are essential for ongoing research in discovery proteomics and aging studies. Interested vendors must submit a capability statement detailing their qualifications, including employee numbers and relevant experience, by January 17, 2025, at 5:00 PM EST, to Iris Merscher at iris.merscher@nih.gov. This notice is a Sources Sought announcement and does not constitute a solicitation for proposals.
    A--National Gene Vector Biorepository
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health (NIH), is seeking proposals for the National Gene Vector Biorepository (NGVB) contract, aimed at supporting gene therapy research for the National Heart, Lung, and Blood Institute (NHLBI). The contract will involve archiving biological specimens, conducting DNA and RNA extractions, and developing assays, while ensuring compliance with FDA regulations and Good Laboratory Practices (GLP). This initiative is critical for advancing gene therapy capabilities and enhancing research resources, with an expected proposal submission deadline of January 10, 2025, and a revised due date for proposals set at 2:00 PM EST on January 15, 2025. Interested parties can contact Ethan J. Mueller at ethan.mueller@nih.gov or +1 301 496 2153 for further information.
    SOURCES SOUGHT: Automated Cell Dissociation Apparatus
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified small businesses to provide an automated cell dissociation apparatus for the National Institute on Aging's Laboratory of Neurogenetics. The primary objective of this procurement is to acquire equipment capable of isolating single nuclei from human and mouse brain tissues, which is crucial for advancing research on neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Parkinson's disease, and Alzheimer's disease. The preferred model for this apparatus is the S2 Genomics Singulator 100 Cell Dissociation Platform, which must meet specific requirements including bench-top compatibility, single-use cartridges, and customizable software for protocol adjustments. Interested companies must submit their capability statements by January 17, 2025, to Rashiid Cummins at rashiid.cummins@nih.gov, ensuring they include all necessary documentation and adhere to the specified format.
    Decoding reagents, consumables, cell segmentation kits, sample prep and stand alone custom gene panel
    Active
    Agriculture, Department Of
    The Department of Agriculture, specifically the Agricultural Research Service, is seeking quotes for a range of decoding reagents, consumables, and custom gene panels necessary for conducting spatial transcriptomics research on avian influenza in chicken lungs. The procurement includes items such as Xenium Decoding Reagents, Advanced Panel Upgrades, and Cell Segmentation Kits, which are critical for analyzing the impact of the virus on various cell types and their transcriptomes. This acquisition is part of a broader effort to enhance understanding of viral effects on poultry health, with a firm fixed-price contract anticipated to be awarded based on the Lowest Price Technically Acceptable (LPTA) evaluation method. Interested vendors must submit their quotes electronically to Brian Brusky at brian.brusky@usda.gov by 5:00 PM Central Time on January 17, 2025, and ensure they are registered in the System for Award Management (SAM) prior to submission.