The Defense Advanced Research Projects Agency (DARPA) is seeking innovative solutions for space-qualified nuclear thermal rocket propulsion engine design and integration through a Request for Information (RFI). This initiative aims to identify sources capable of providing advanced capabilities in engine design, modeling, simulation, and autonomous control, with a focus on safety analysis for nuclear launch authorization from the Department of Defense. The RFI is part of DARPA's collaboration with NASA's DRACO program, which seeks to enhance U.S. military capabilities and support future human missions to Mars by developing a compact nuclear thermal rocket engine fueled by high-assay low-enriched uranium (HALEU). Responses to this RFI are due by January 20, 2025, and interested parties can contact the TTO BAA Coordinator at DARPA-SN-25-21@darpa.mil for further information.