Intent to Sole Source - DNA Purification System
ID: 1204892Q0121Type: Special Notice
Overview

Buyer

AGRICULTURE, DEPARTMENT OFFOREST SERVICEPACIFIC NORTHWEST RESEARCH STATIONPORTLAND, OR, 97205, USA

NAICS

Testing Laboratories and Services (541380)

PSC

LABORATORY EQUIPMENT AND SUPPLIES (6640)
Timeline
    Description

    The Department of Agriculture's Forest Service, specifically the Pacific Northwest Research Station, intends to award a sole-source contract for the acquisition of a Thermo Scientific™ KingFisher™ Duo Prime Purification System. This specialized equipment is essential for projects focused on detecting invasive forest pathogens, which require high-quality DNA extraction from complex samples such as soil and water. The KingFisher system, utilizing advanced magnetic bead technology, allows for efficient processing of up to 96 samples simultaneously, addressing previous challenges faced with conventional DNA extractors. For further inquiries, interested parties can contact Nola Wisenor at nola.wisenor@usda.gov.

    Point(s) of Contact
    Files
    Title
    Posted
    The Thermo Scientific KingFisher Duo Prime Purification System is designed to efficiently isolate DNA, RNA, and proteins from various starting materials, such as blood, tissue, and cell cultures, making it suitable for laboratories focused on nucleic acid purification and proteomics. This compact instrument utilizes automated magnetic bead technology for high recovery rates and reproducibility, and it has a small laboratory footprint. Key features include an optional bar-code reader for sample tracking and compatibility with KingFisher Pure isolation kits and customizable protocols via BindIt Software. The package includes a one-day SmartStart Orientation conducted by a Field Application Scientist to ensure swift setup and proper reagent selection tailored to laboratory needs. This document is part of federal RFPs aimed at acquiring equipment for scientific research, signifying a focus on enhancing laboratory capabilities and ensuring efficient workflow in nucleic acid handling and analysis.
    The USDA Forest Service's Pacific Northwest Research Station seeks approval for the sole-source purchase of a Thermo Scientific™ KingFisher™ Duo Prime Purification System with SmartStart, essential for BIL projects ERR09 and ERR10. These projects focus on developing technologies for detecting invasive forest pathogens across various climate zones and biological samples. The need for high-quality DNA extraction from complex samples, such as soil and water, is critical for the project's success. Previous attempts using conventional DNA extractors yielded unsatisfactory results. The KingFisher system, unique to ThermoFisher Scientific, utilizes magnetic bead technology, enabling efficient processing of up to 96 samples simultaneously. The purchase is urgent as delays jeopardize project deadlines and outcomes, underscoring the system's importance for advancing research in forest pathology and pathogen detection. This procurement aligns with federal guidelines for sole-source acquisitions due to the specialized nature of the required equipment and its proven efficacy in similar research settings.
    The USDA Forest Service's Pacific Northwest Research Station seeks approval to procure a Thermo Scientific™ KingFisher™ Duo Prime Purification System from Fisher Scientific™ for two research projects (ERR09 and ERR10) aimed at detecting invasive forest pathogens. The projects require high-quality DNA extraction from various biological samples, including soil and plant tissues. Previously attempted conventional extraction methods yielded unsatisfactory results, thus necessitating the unique capabilities of the KingFisher system, which utilizes automated magnetic bead technology for efficient DNA isolation. This system can process 96 samples simultaneously, enhancing productivity and supporting the urgent timeline of the projects. Fisher Scientific™ is the sole manufacturer of this equipment, and extensive attempts to identify alternative, comparable products failed, confirming its unique suitability for these research needs. The procurement is critical to ensure the project deadlines are met and the required high-quality DNA is obtained for further analysis and progression in scientific studies.
    Lifecycle
    Similar Opportunities
    Qiagen Real Time Semi-Quantitative PCR (RT-qPCR) and Digital PCR (dPCR) System or Equal
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking proposals for a Qiagen Real Time Semi-Quantitative PCR (RT-qPCR) and Digital PCR (dPCR) System or an equivalent product. The procurement aims to support research into neurodegenerative diseases and retroviral infections, requiring a system with multiplex capability for detecting five gene targets, automated operation, low variability in results, and a compact size not exceeding 16” x 28” x 20”. Proposals must be submitted by 9:00 a.m. Eastern Time on September 17, 2024, and should include a completed copy of certain FAR clauses and the Unique Entity ID. For further inquiries, interested parties can contact Frederick Weddington at frederick.weddington@nih.gov or by phone at 301-594-6835.
    ULTRACENTRIFUGE
    Active
    Interior, Department Of The
    The U.S. Department of the Interior, specifically the U.S. Geological Survey, is seeking quotes for the procurement of one Beckman Coulter Optima XE-90 Ultracentrifuge or an equivalent model. This equipment is essential for analytical laboratory operations, requiring specific technical specifications such as speed, capacity, and cooling system features. The procurement process is governed by federal regulations, emphasizing compliance and transparency, with a submission deadline for quotes set for September 17, 2024, and expected delivery by October 31, 2024. Interested vendors should direct their inquiries and quotes to Kekila Keuma at kkeuma@usgs.gov.
    Sequencing Supplies
    Active
    Agriculture, Department Of
    The Department of Agriculture, specifically the Agricultural Research Service, is seeking quotes for Sequencing Supplies under a Total Small Business Set-Aside contract. The procurement includes essential genomic analysis tools, specifically the TruSeq DNA Nano Low Throughput Library Prep Kit, MiSeq Reagent Kit v3, and IDT for Illumina – TruSeq DNA UD Indexes v2, which are critical for efficient genomic library preparation and sequencing. These supplies are vital for research and clinical applications, ensuring high data quality and throughput in genomic studies. Interested vendors must submit their quotes electronically to Joel Maas at joel.maas@usda.gov by 5:00 PM Eastern Time on September 16, 2024, and must be registered in the System for Award Management (SAM) to be eligible for award consideration.
    Next-Generation Sequencing (NGS) Liquid Handling Systems – Brand Name or Equal
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotes for two Next-Generation Sequencing (NGS) Liquid Handling Systems to enhance research capabilities at its Bethesda, Maryland campus. These systems are essential for high-throughput processing in infectious disease research, particularly for single cell-based antibody discovery and RNA/DNA processing, which are critical for pandemic preparedness. Interested vendors must submit their quotes by 12:00 pm EST on September 26, 2024, including detailed specifications and compliance with federal regulations, to Daveta H. Brown at daveta.brown@nih.gov.
    Short-Read Next-Generation DNA Sequencing System
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotations for a Short-Read Next-Generation DNA Sequencing System to enhance its laboratory capabilities for rare variant discovery. The system must meet stringent requirements, including high accuracy (≥90%), compatibility with existing library formats, and the ability to detect variants down to 0.001%, along with specific physical dimensions and training for researchers. This procurement is crucial for advancing scientific research capabilities within the NIH and will be processed under Simplified Acquisition Procedures, with no set-aside for small businesses. Interested vendors should submit their quotes, including pricing and compliance with technical specifications, to Matt Lear at matt.lear@nih.gov by the specified deadline.
    BD FACS Symphony S6 Cell Sorter (Brand Name or Equal)
    Active
    Health And Human Services, Department Of
    The National Institutes of Health (NIH), specifically the National Institute of Allergy and Infectious Diseases (NIAID), is seeking to procure one (1) BD FACSymphony S6 SE Cell Sorter System (or equal) along with a twelve-month maintenance agreement for parts and labor. This procurement is critical as the existing cell sorter is nearing the end of its life cycle, and the new system must meet specific requirements, including compatibility with FlowJo software and advanced operational safety features, to support high-containment research involving infectious samples. Interested vendors are required to submit comprehensive quotes by September 19, 2024, with evaluations focusing on technical acceptability, past performance, and price to ensure the best value for the government. For further inquiries, vendors can contact Linda Smith at linda.smith2@nih.gov or Christian Brown at christian.brown@nih.gov.
    Sources Sought Additional Open Path FTIR for USDA ARS Kimberly, ID
    Active
    Agriculture, Department Of
    The Department of Agriculture's Agricultural Research Service (USDA ARS) is seeking information from qualified suppliers regarding the availability and capability to provide additional open path FTIR equipment for its facility in Kimberly, Idaho. The procurement aims to acquire 22 advanced FTIR systems that seamlessly integrate with existing Cerex monitoring systems, featuring specifications such as a wavelength range of 600-4200 cm-1 and the ability to analyze over 350 gas compounds simultaneously. This initiative is crucial for enhancing environmental monitoring in agricultural settings, ensuring reliable performance in extreme climates. Interested vendors, particularly small businesses, are encouraged to submit capability statements by the specified deadline to Michael Sherlock at michael.sherlock@usda.gov, as this notice is part of market research and does not constitute a solicitation for proposals.
    Automated Liquid Handling Systems– Brand Name or Equal
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotes for the procurement of two automated liquid handling systems, either brand name or equal, to support the Vaccine Production Program (VPP) at the National Institute of Allergy and Infectious Diseases (NIAID). These systems are critical for high-throughput, microscale protein purification and product characterization, which are essential for developing vaccines against various pathogens, including HIV and SARS-COV-2. Interested vendors must submit their quotes by 12:00 PM EST on September 23, 2024, to Daveta H. Brown at daveta.brown@nih.gov, ensuring compliance with all specified requirements and regulations outlined in the solicitation documents.
    NIEHS - Exodus H-600
    Active
    Health And Human Services, Department Of
    The National Institute of Environmental Health Sciences (NIEHS) intends to negotiate a sole-source contract with Exodus Bio, Inc. for the acquisition of an Exodus H-600 automatic exosome isolation system. This procurement aims to enhance the NIEHS's capabilities in biological product manufacturing, specifically focusing on the isolation of exosomes, which are critical for various research applications in environmental health. The contract, associated with NAICS Code 325414, is expected to include one unit of the specified equipment, with a delivery timeframe of 60 days post-award. Interested parties capable of fulfilling this requirement are encouraged to submit a capability statement via email by September 18, 2024, and inquiries can be directed to Tanya Redfearn at shields3@niehs.nih.gov or by phone at 984-287-3052.
    Liquid Chromatography coupled with High Resolution-Accurate Mass Tandem Mass Spectrometer System (LC-HRAM-MS/MS)
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the Food and Drug Administration (FDA), is seeking quotes for the procurement of a Liquid Chromatography coupled with High Resolution-Accurate Mass Tandem Mass Spectrometer System (LC-HRAM-MS/MS) to enhance the capabilities of the Forensic Chemistry Center (FCC). This advanced system will replace an existing instrument and is crucial for analyzing biotherapeutics, thereby supporting regulatory investigations in food and drug safety. Interested contractors must ensure compliance with stringent technical specifications and are required to submit their quotes electronically by September 17, 2024, to Nina Montgomery at nina.montgomery@fda.hhs.gov. The contract will also include provisions for a trade-in of an older model and a one-year service warranty, with delivery and installation expected within 90 days of award.