The Department of Health and Human Services, specifically the National Institutes of Health, is seeking proposals for the development of novel tools and devices to improve animal welfare and support animal model research. The goal is to enhance the management of individual animals and animal colonies, as well as monitor and control environmental conditions that can affect research outcomes. The variation in environmental factors between different animal facilities has been identified as a source of irreproducibility in animal research. Therefore, the agency is looking for devices that can accurately monitor challenging environmental conditions such as humidity, vibrations, odors, and ultrasonic noise. Additionally, there is a need for noninvasive or minimally invasive bio-logging devices for real-time monitoring of animal behavior, food/water consumption, and bodily functions. The development of new software that can combine data from different monitoring devices and link to existing databases is also desired. The agency emphasizes the importance of innovation and encourages the adaptation of technologies from other fields to improve animal research. The solicitation is open for Small Business Technology Transfer (STTR) projects, and the application due dates are provided on the grants.gov website. For more information, interested parties can visit the solicitation agency URL.