Technology to facilitate characterization of the exposome in under-resourced populations for AD/ADRD Studies
ID: NIH/NIA 010Type: BOTH
Overview

Topic

Technology to facilitate characterization of the exposome in under-resourced populations for AD/ADRD Studies

Agency

Department of Health and Human ServicesNational Institutes of Health

Program

Type: SBIRPhase: BOTHYear: 2023

Topic Link

https://www.sbir.gov/node/2451723

Additional Information

https://sam.gov/opp/aa72581c848947f0b61c15062e604862/view
Timeline
  1. 1
    Release Aug 25, 2023 12:00 AM
  2. 2
    Open Aug 25, 2023 12:00 AM
  3. 3
    Next Submission Due Nov 14, 2023 12:00 AM
  4. 4
    Close Nov 14, 2023 12:00 AM
Description

The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking proposals for a Small Business Innovation Research (SBIR) contract related to the technology to facilitate characterization of the exposome in under-resourced populations for AD/ADRD studies. The goal of this research is to develop technologies that enable remote or self-sampling, allowing greater participation of under-resourced populations in research on age-related diseases such as Alzheimer's and related dementias. The research aims to address the difficulties in collecting environmental and biological samples from these populations, which often carry a high burden of these diseases. The solicitation emphasizes the need for remote sampling tools that enable self- or caregiver-collected specimens for longitudinal population-based studies, linking environmental exposures to molecular changes associated with adverse aging and the development of Alzheimer's and related dementias. Additionally, there is a need for portable air sampling devices that capture physical and bioaerosols in liquid media to maintain their viability. The technologies should be user-friendly and enable sample capture at the point of exposure, with the samples shipped back to a central lab facility for analysis. The solicitation encourages proposals that adhere to the specified budget amounts and project periods. The anticipated awards include 1 to 2 projects, with a budget of $500,000 for Phase I (12 months) and $2,500,000 for Phase II (2 years). Fast-Track and Direct-to-Phase II proposals will also be accepted.

Files
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