Prophylactics/Therapeutics for Neurotoxin Exposure
ID: CBD254-004Type: BOTH
Overview

Topic

Prophylactics/Therapeutics for Neurotoxin Exposure

Agency

Agency: DODBranch: CBD

Program

Type: SBIRPhase: BOTH

Topic Link

https://www.dodsbirsttr.mil/topics-app/

Additional Information

https://www.dodsbirsttr.mil/topics-app/
Timeline
    Description

    The Department of Defense (DOD) is seeking innovative solutions through the Small Business Innovation Research (SBIR) program to develop prophylactics and therapeutics for neurotoxin exposure, specifically targeting organophosphorus compounds used in chemical warfare. The objective is to create a biological agent that can prevent illness from exposure to G-type and V-type nerve agents, with a focus on stability, efficacy, and pharmacokinetics for both prophylactic and therapeutic applications. This initiative is crucial for enhancing the safety of military personnel on the battlefield and protecting civilians from potential chemical attacks. Interested parties should note that the solicitation will open on January 29, 2025, and close on February 26, 2025, with further details available at the DOD SBIR website.

    Files
    Title
    Posted
    PDF.html
    Similar Opportunities
    PEO SOF Warrior - Secure and Protect Infrastructure through Cyber-threat Emulation (SPICE) Open Topic -
    DOD
    The Department of Defense, specifically the Program Executive Office for Special Operations Forces (PEO SOF Warrior), is seeking innovative proposals under the SBIR program for the Secure and Protect Infrastructure through Cyber-threat Emulation (SPICE) Open Topic. The objective is to develop advanced cyber capabilities that enhance offensive, defensive, and evaluative activities in support of Special Operations, focusing on areas such as cyber-related technologies for remote operational control, denial and disruption of information systems, and alternative access mechanisms to protected networks. This initiative is crucial for maintaining operational superiority in an evolving cyber landscape, with a feasibility study required in Phase I to assess potential technologies, followed by prototype development in Phase II. Interested parties should note that the solicitation is set to open on June 25, 2025, with proposals due by July 23, 2025, and can find more information at the provided source link.
    Cognitive Mapping for Counter-WMD Operations -
    DOD
    The Defense Threat Reduction Agency (DTRA) is seeking innovative solutions through the Small Business Innovation Research (SBIR) program to develop cognitive mapping algorithms aimed at enhancing counter-weapons of mass destruction (WMD) operations. The objective is to create 2D or 3D maps of building interiors by integrating architectural knowledge into traditional Simultaneous Localization and Mapping (SLAM) techniques, thereby improving situational awareness in GPS-denied environments. This initiative is critical for enabling DTRA and its partners to execute missions effectively, particularly in complex structures where conventional mapping methods may fall short. Interested parties should note that the solicitation is set to open on June 25, 2025, with applications due by July 23, 2025, and further details can be found at the DOD SBIR website.
    Blast Injury Simulation in Armored Vehicles Affected by Blast Pressure, Shaped Charge, or Dense Inert Projectile Weapons -
    DOD
    The Department of Defense, through the Defense Threat Reduction Agency (DTRA), is seeking proposals for the Small Business Innovation Research (SBIR) program focused on developing computational tools for simulating blast injuries in armored vehicles. The objective is to create high-fidelity modeling frameworks that can quantify the interior environments of vehicles exposed to various explosive threats, including shaped charges and high explosives, to predict potential injuries to occupants. This initiative is crucial for providing military command surgeons and battalion commanders with insights into injury types and severities in combat scenarios. Proposals are due by July 23, 2025, with the opportunity opening on June 25, 2025, and further details can be found at the DOD SBIR website.
    Integration of Wave Relay API Features into the Thales InterSense IS-1500 Visual Inertial Tracking Software -
    DOD
    The Defense Threat Reduction Agency (DTRA) is seeking innovative software solutions through the Small Business Innovation Research (SBIR) program to integrate Wave Relay API features into the Thales InterSense IS-1500 Visual Inertial Tracking Software. The primary objective is to enhance local positioning capabilities for uncrewed and worn sensors during tactical operations by leveraging RF signal information, ensuring accuracy within 1 meter in a 300-meter by 300-meter area without GPS reliance, particularly in low-light conditions. This technology is crucial for improving the reliability of positioning solutions in GPS-denied environments, especially for Chemical, Biological, Radiological, and Nuclear (CBRN) sensor operations. Interested parties should note that the solicitation is set to open on June 25, 2025, with applications due by July 23, 2025, and can find more information at the DOD SBIR website.
    PEO SOF Warrior - Secure and Protect Infrastructure through Cyber-threat Emulation (SPICE) Open Topic -
    DOD
    The Department of Defense, specifically the U.S. Special Operations Command (USSOCOM), is seeking innovative proposals under the SBIR program for the Secure and Protect Infrastructure through Cyber-threat Emulation (SPICE) Open Topic. The objective is to develop advanced cyber capabilities that enhance offensive, defensive, and evaluative operations in support of Special Operations, focusing on techniques and technologies that improve cyber-related capabilities, including remote operational control and network reconnaissance. This initiative is critical for maintaining operational effectiveness in an evolving cyber landscape, with applications extending to military, intelligence, law enforcement, and commercial sectors. Interested parties must submit their proposals by July 23, 2025, with further details available at the provided solicitation links.
    Photonic Integrated NV Center in Diamond Vector Magnetometers -
    DOD
    The Department of Defense is seeking proposals for the development of a Photonic Integrated Nitrogen Vacancy Center in Diamond Vector Magnetometer through the Small Business Innovation Research (SBIR) program. The objective is to create an on-chip NVD sensor that minimizes size, weight, and power requirements while simplifying fabrication processes, aiming for a sensitivity of 100 picoTesla/Hz1/2 at 1 Hz and an accuracy of 1 nanoTesla. This technology is crucial for applications in magnetic navigation and anomaly detection, with potential dual-use applications for the Department of Defense following successful validation. Interested parties should note that the Phase I funding amount is capped at $314,363 for a 12-month period, while Phase II funding can reach up to $2,095,000 over 24 months, with proposals due by July 23, 2025. For more information, visit the solicitation agency's website at https://www.dodsbirsttr.mil/topics-app/.
    Faraday optical isolator on a photonic integrated laser circuit -
    DOD
    The Department of Defense (DOD) is seeking proposals for the Small Business Innovation Research (SBIR) program focused on developing a Faraday optical isolator integrated on a photonic laser circuit. The objective is to create a fully integrated optical isolator that achieves greater than 25 dB of isolation and less than 2 dB of insertion loss, addressing the current limitations of off-chip solutions that complicate packaging and reduce efficiency in laser systems. This technology is crucial for applications in quantum technology, telecommunications, and directed energy systems. The Phase I funding amount is capped at $314,363 for a 12-month period, while Phase II funding can reach up to $2,095,000 over 24 months. Proposals are due by July 23, 2025, with the opportunity opening on June 25, 2025. For more information, interested parties can visit the DOD SBIR website at https://www.dodsbirsttr.mil/topics-app/.
    PEO SOF Warrior - Visual Augmentation Systems (VAS) Open Topic -
    DOD
    The Department of Defense, through the Special Operations Command (SOCOM), is seeking innovative solutions under the Small Business Innovation Research (SBIR) program for the Visual Augmentation Systems (VAS) Open Topic. The primary objective is to develop technologies that enhance user vision through various electromagnetic spectrums, including visible and infrared ranges, with applications for helmet-mounted, weapon-mounted, and handheld devices. This initiative is crucial for improving operational effectiveness and lethality in military environments, particularly during low-light conditions. Interested parties should prepare to submit proposals by July 23, 2025, following a feasibility study phase, with further details available on the official SBIR website.
    Underwater Sensing in Surf Zone Environments -
    DOD
    The Department of Defense, specifically the U.S. Army, is seeking proposals for the Small Business Innovation Research (SBIR) program focused on developing an underwater sensing system for surf zone environments. The objective is to create a portable sensor capable of detecting bathymetry and underwater hazards in shallow, bubbly conditions, which is critical for safe maritime operations and logistics support in contested regions. This technology is particularly important for enhancing situational awareness during over-the-shore operations, where traditional sensing methods are hindered by environmental factors such as surf zone bubbles. Proposals for Phase I are due by August 20, 2025, with a funding amount of up to $250,000 for a six-month performance period. Interested parties can find more information and submit proposals through the official SBIR website.
    Underwater Sensing in Surf Zone Environments -
    DOD
    The Department of Defense, specifically the U.S. Army, is seeking proposals for the development of an underwater sensing system optimized for surf zone environments as part of the Small Business Innovation Research (SBIR) program. The objective is to create a portable underwater sensor capable of detecting bathymetry and underwater hazards in shallow, bubbly conditions, which are critical for safe maritime operations and logistics support in contested regions. This technology is particularly important for enhancing situational awareness during over-the-shore operations, where traditional sensing methods are hindered by environmental factors such as surf zone bubbles. Proposals for Phase I are invited with a funding limit of $250,000 for a six-month performance period, with a submission deadline of August 20, 2025. Interested parties can find more information and submit proposals through the official SBIR website.