The National Institutes of Health (NIH) is offering the INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome, aimed at enhancing health and quality of life for individuals with Down syndrome. This funding opportunity invites researchers to propose innovative exploratory and developmental projects that address critical needs identified in the INCLUDE Project objectives, potentially leading to breakthroughs in biomedical, behavioral, or clinical research. The total estimated program funding is $1 million, with individual awards ranging from $50,000 to $200,000, and the application process is open to a diverse range of eligible applicants, including tribal governments and community-based organizations. Interested parties should contact Dr. Melissa Parisi at 301-728-1861 or via email at parisima@mail.nih.gov for further information, with applications due by February 19, 2026, and awards expected to be announced by September 1, 2026.