The Department of Energy's Office of Science has announced a funding opportunity titled "Artificial Intelligence and Machine Learning Applied to Nuclear Science and Technology" (DE-FOA-0003458), aimed at supporting innovative research and development projects that leverage AI and machine learning to optimize operations in nuclear physics. The initiative seeks applications focused on enhancing accelerator and detector performance, addressing challenges in data analysis, simulations, and control within current and future nuclear physics facilities. With a total funding pool of up to $22 million, individual awards will range from $200,000 to $3.5 million, and projects are expected to span a two-year period. Interested applicants, including all domestic institutions except certain nonprofit organizations, must submit a Letter of Intent and are encouraged to promote inclusivity in their research efforts. For further inquiries, applicants can contact Dr. Manouchehr Farkhondeh at manouchehr.farkhondeh@science.doe.gov or by phone at 301-903-4398. The application deadline is January 14, 2025.