DoD Peer Reviewed Medical Research Program, Technology/Therapeutic Development Award
ID: 358887Type: Posted
Overview

Buyer

Dept. of the Army -- USAMRAA (DOD-AMRAA)

Eligible Applicants

Unrestricted

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/358887
Timeline
    Description

    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Peer Reviewed Medical Research Program (PRMRP) Technology/Therapeutic Development Award (TTDA) to support the translation of promising preclinical findings into clinical applications for military personnel, veterans, and their families. This grant aims to facilitate the development of products that address military-related health challenges, including prevention, detection, diagnosis, treatment, or quality of life improvements, with a focus on innovative approaches in areas such as autoimmune disorders and infectious diseases. With an estimated total program funding of approximately $41.25 million available for up to 11 awards, applicants must submit a two-step application process, including a pre-application and a full application, by the closing date of July 21, 2025. For further inquiries, interested parties can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.

    Point(s) of Contact
    help@eBRAP.org
    Files
    Title
    Posted
    HT942525PRMRPTTDA-GG.pdf
    The Department of Defense's Defense Health Program is announcing the FY25 Peer Reviewed Medical Research Program for the Technology/Therapeutic Development Award (TTDA), focusing on translating promising preclinical findings into clinical applications for military personnel, veterans, and their families. This funding opportunity, with approximately $41.25 million available to support up to 11 applications, includes direct cost caps of $2.5 million and a maximum period of performance of four years. Eligible applicants include both extramural and intramural organizations, and the project must align with one of the designated FY25 topic areas addressing military-related health challenges. The application process consists of a two-step submission: a pre-application and a full application containing detailed project plans and evidence of preliminary data. Proposed research must demonstrate relevance to military health and progress towards regulatory filing or clinical use, emphasizing innovative approaches in areas such as autoimmune disorders, cardiovascular health, infectious diseases, and rare conditions. Compliance with submission requirements, including registration on relevant government platforms, is essential for consideration. This program aims to foster advancements in medical technologies directly benefiting the unique healthcare needs of service members and their families.
    Similar Opportunities
    DoD Military Burn, Technology/Therapeutic Development Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a funding opportunity via the Military Burn Research Program (MBRP) for the Technology/Therapeutic Development Award (TTDA). This grant aims to support the development of tangible products, such as medical devices or drugs, and knowledge products that enhance burn care for military personnel in austere operational environments. The program allocates approximately $3.4 million for two awards, with a maximum funding cap of $1.7 million per project, and proposals must align with specific focus areas related to burn prevention and treatment strategies in combat scenarios. Interested applicants should note that a pre-application is due by June 23, 2025, followed by a full application deadline of September 8, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Peer Reviewed Medical Research Program, Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity under the Peer Reviewed Medical Research Program (PRMRP) for the fiscal year 2025, specifically for the Clinical Trial Award (CTA). This program aims to support the rapid implementation of clinical trials that can significantly impact the treatment or management of diseases relevant to military health, with a focus on areas such as autoimmune disorders, cardiovascular health, infectious diseases, and neuroscience. Approximately $32 million is available for this initiative, with an expected four awards, each capped at $8 million, and applications are due by July 21, 2025. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507 for further assistance.
    DOD Amyotrophic Lateral Sclerosis, Therapeutic Development Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Development Award (TDA) to support innovative research aimed at developing therapies for Amyotrophic Lateral Sclerosis (ALS). This grant program seeks applications that demonstrate proof-of-concept efficacy in preclinical models of ALS, with a focus on empirical therapeutic studies and the development of mechanism-specific biomarkers to enhance trial design and patient selection. With an estimated total funding of approximately $9.8 million, the program anticipates awarding about four grants, each capped at $1.5 million for a maximum duration of three years. Interested applicants must submit a pre-application by June 6, 2025, followed by a full application due by August 27, 2025. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Duchenne Muscular Dystrophy, Clinical/Translational Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity for the Duchenne Muscular Dystrophy Research Program's Clinical/Translational Research Award (CTRA) for fiscal year 2025. This funding initiative aims to support advanced translational research that accelerates promising ideas in Duchenne muscular dystrophy (DMD) into clinical applications, particularly focusing on therapies effective across all age groups, including infants and nonambulatory individuals. With an estimated total program funding of approximately $8.56 million, the program anticipates awarding around five grants, encouraging collaborations with early-career investigators and requiring applications to include preliminary data relevant to DMD. Interested applicants should note that a pre-application is due by July 25, 2025, with full applications due by August 8, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Peer Reviewed Cancer, Idea Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the fiscal year 2025 Peer Reviewed Cancer Research Program (PRCRP) Idea Award to support innovative cancer research that prioritizes military health. This grant aims to fund high-risk, high-reward proposals that focus on specific cancer types relevant to Service Members, Veterans, and their families, with an emphasis on introducing new paradigms in cancer care and addressing environmental exposure risks. With an estimated total program funding of approximately $14 million, the program anticipates awarding around 25 projects, each with a maximum funding limit of $560,000 for a duration of up to two years. Interested applicants must submit a pre-application by June 20, 2025, followed by a full application due by September 25, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Amyotrophic Lateral Sclerosis, Therapeutic Idea Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Therapeutic Idea Award (TIA) under the fiscal year 2025 Amyotrophic Lateral Sclerosis Research Program (ALSRP). This grant aims to support innovative, high-risk research proposals focused on drug or therapy development for Amyotrophic Lateral Sclerosis (ALS), with an emphasis on generating preliminary data for future therapeutic investigations. The program has a total funding amount of approximately $10.8 million, with individual awards capped at $600,000 and a performance period not exceeding two years. Interested applicants must submit pre-applications by June 6, 2025, and full applications by August 27, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Peer Reviewed Cancer, Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity for the fiscal year 2025 under the Peer Reviewed Cancer Research Program (PRCRP) Clinical Trial Award (CTA). This grant aims to support the rapid implementation of clinical trials that have the potential to significantly impact cancer treatment, specifically targeting designated cancer types relevant to military health. The program emphasizes the importance of advancing cancer research to benefit service members, veterans, and their families, with funding available for projects ranging from initial proof-of-concept trials to large-scale phase III trials, capped at a total cost of $4.2 million over a maximum performance period of four years. Interested applicants must submit pre-applications by June 20, 2025, followed by full applications due by September 25, 2025, and can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.
    DoD Toxic Exposures Translational Research Partnership Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Toxic Exposures Translational Research Partnership Award (TRPA) to support collaborative research addressing military-related toxic exposures. This grant aims to foster interdisciplinary partnerships among Principal Investigators (PIs) to advance translational research that integrates basic science with clinical applications, focusing on health care products, interventions, and clinical practice guidelines. Approximately $4.48 million is available for two awards, with each award capped at $2.24 million, and applications are due by October 16, 2025. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507 for further information.
    DOD Peer Reviewed Cancer, Impact Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Peer Reviewed Cancer Research Program (PRCRP) Impact Award to support high-impact research aimed at improving clinical cancer care relevant to military health. This grant seeks mature research projects that demonstrate potential for near-term benefits in cancer treatment and patient outcomes, particularly focusing on specific cancer types such as bladder, blood, and brain cancers, while excluding melanoma and breast cancers. The program emphasizes the importance of preliminary data, collaboration with Department of Defense (DOD) and Veterans Affairs (VA) entities, and rigorous study designs to advance cancer detection and treatment for service members and their families. The estimated total program funding is $45.5 million, with individual awards capped at $1.4 million for single Principal Investigator applications and $1.75 million for partnering applications, over a maximum period of three years. Interested applicants must submit a pre-application by September 25, 2025, and can contact the CDMRP Help Desk at help@eBRAP.org for further assistance.
    Alzheimer’s Research Program Transforming Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Alzheimer's Research Program Transforming Research Award to support innovative research aimed at reducing the risk of Alzheimer's disease and related dementias (AD/ADRD). This grant opportunity encourages diverse applicants, including for-profit, non-profit, and academic institutions, and emphasizes the necessity of community collaboration, particularly for clinical research projects. With an estimated total program funding of $4 million, the program anticipates awarding approximately four grants, each providing up to $1 million over a maximum of three years. Interested applicants must submit a pre-application by June 12, 2025, followed by a full application due by August 29, 2025. For further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.