The National Institutes of Health (NIH) has announced a funding opportunity titled "The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)" aimed at supporting innovative research that explores how work influences health outcomes and disparities among various populations. This initiative seeks to identify and characterize the pathways through which employment and occupational factors affect health, particularly focusing on underrepresented groups and issues related to mental health and substance use. Eligible applicants include a wide range of organizations such as higher education institutions, community-based organizations, and tribal governments, with no budget cap for proposals that reflect project needs. Applications will be accepted starting January 5, 2025, with awards expected to commence in July 2025; interested parties can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.