The National Institutes of Health (NIH), through the National Institute of Mental Health (NIMH), issued a Notice of Funding Opportunity (NOFO) focused on the AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional). This initiative aims to establish HIV/AIDS Research Centers (ARCs) that enhance research infrastructure and promote interdisciplinary studies addressing the intersection of mental health and HIV/AIDS. The centers will concentrate on innovative research in various domains including biostatistics, prevention, and implementation science, with priority given to addressing health disparities and systemic inequities in HIV care. Applications are invited for new, renewal, or resubmission grants with a budget cap of $1.5 million annually for up to five years. Eligible applicants include educational institutions, non-profits, and local governments that can demonstrate substantial research capacity. Key dates include a submission opening on July 25, 2024, with various review cycles extending through 2027. Additionally, applicants must follow specific guidelines for submission and data management, including sharing outcomes through the NIMH Data Archive. This funding opportunity seeks to foster collaboration across sectors and enhance the impact of HIV research while aligning with national strategies for HIV prevention and care. The overall aim is to build robust capabilities that drive forward the understanding and treatment of HIV/AIDS.