The National Institutes of Health (NIH), through the National Center for Advancing Translational Sciences (NCATS), is offering the Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) grant to foster innovative technology development aimed at enhancing therapeutic processes. This funding opportunity specifically targets high-risk, early-stage research projects that may lack preliminary data but show significant potential for advancements in translational science, with a focus on addressing inefficiencies in therapeutic development. The program is critical for accelerating treatment delivery across various diseases and encourages a diverse applicant pool, including institutions such as higher education, nonprofits, and small businesses. Applicants may request up to $275,000 in direct costs over a two-year project duration, with a submission deadline of June 19, 2025. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov or visit the additional information link at https://grants.nih.gov/grants/guide/pa-files/PAR-23-177.html.