The National Science Foundation (NSF) is offering a grant opportunity titled "Emerging Frontiers in Research and Innovation (EFRI): Biocomputing through EnGINeering Organoid Intelligence (BEGIN OI)." This initiative aims to support foundational and transformative research focused on the design, engineering, and fabrication of organoid systems capable of dynamic information processing while interfacing with non-living systems. The EFRI program seeks proposals that present potentially transformative ideas with significant long-term impacts on national needs or grand challenges, and it is coordinated with multiple NSF directorates to foster interdisciplinary collaboration. The estimated total program funding is $30 million, with proposals due by December 12, 2024. For further inquiries, interested applicants can contact NSF grants.gov support at grantsgovsupport@nsf.gov.