The National Institutes of Health (NIH) is offering the Maximizing Investigators' Research Award (MIRA) for Early Stage Investigators (ESI) to support a comprehensive research program within an investigator's laboratory that aligns with the mission of the National Institute of General Medical Sciences (NIGMS). This funding opportunity encourages early independence in research careers by providing substantial funding of up to $250,000 per year for a maximum of five years, allowing investigators to explore innovative research avenues without the burden of preliminary data requirements. Eligible applicants must be NIH-defined ESIs and are required to submit a Plan for Enhancing Diverse Perspectives (PEDP) to promote inclusivity in research efforts. Interested parties can find more information and apply electronically through Grants.gov, with the application deadline set for February 3, 2026. For inquiries, applicants may contact NIH Grants Information at grantsinfo@nih.gov.