The National Institutes of Health (NIH) has issued a funding opportunity for the Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) program. This initiative aims to enhance research education for federally recognized American Indian/Alaska Native (AI/AN) entities by developing and implementing training for individuals pursuing biomedical degrees. The program seeks to address health disparities experienced by AI/AN populations by building a workforce equipped to conduct culturally appropriate research. The funding will support a two-phase award: a development phase (UE5) for establishing program infrastructure and a training phase (T34) for supporting undergraduate trainees. Eligible entities include tribal colleges or universities and federally recognized Tribes. Through this initiative, the NIH aims to increase representation and leadership in AI/AN health research, facilitating mentoring and networking opportunities for trainees. The total award period can extend to seven years, with funding contingent on the submission of meritorious applications. The program underscores the importance of developing technical, operational, and professional skills necessary for successful careers in the biomedical research workforce.