The National Institutes of Health (NIH) has released a Notice of Funding Opportunity (NOFO) for applications regarding the Change of Recipient Organization for specific NIH grant types. This funding opportunity allows current organizations holding NIH grants to request a change in their recipient organization while ensuring that the proposed research remains within the scope of the original grant. Applications for multi-project and complex codes must be submitted on paper, whereas single-project applications can be submitted electronically. Key details include the requirement for all applications to adhere to the NIH Grants Policy Statement, where prior approval from the Grants Management Specialist is necessary. The eligibility for applicants spans various entities, including higher education institutions, nonprofits, and local governments. Additionally, various NIH Institutes and Centers are involved, and co-funding may occur through certain offices. The submission process emphasizes strict adherence to guidelines, with specific attention required for proposed research involving human subjects or animals. Ultimately, NIH aims to support the continuum of health research by facilitating institutional changes that align with programmatic goals while maintaining regulatory compliance and research integrity.