DoD Multiple Sclerosis, Investigator-Initiated Research Award
ID: 353638Type: Posted
Overview

Buyer

Dept. of the Army -- USAMRAA (DOD-AMRAA)

Eligible Applicants

Unrestricted

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY24 Multiple Sclerosis Investigator-Initiated Research Award (IIRA) to support high-impact research projects related to multiple sclerosis (MS). This funding opportunity aims to advance innovative research that addresses critical areas within MS, such as central nervous system repair and disease activity correlates, with a total program funding of $6 million and an expected six awards. The initiative is particularly significant for enhancing patient care and quality of life for active duty military personnel, veterans, and the public. Interested applicants must submit pre-applications by June 10, 2024, with full applications due by October 7, 2024; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.

    Point(s) of Contact
    Files
    Title
    Posted
    The Department of Defense (DOD) is announcing the FY24 Multiple Sclerosis Investigator-Initiated Research Award (IIRA) under the Congressionally Directed Medical Research Programs. This funding opportunity aims to support high-impact research relevant to active duty military personnel, veterans, and the public, with a total appropriation of $20 million for FY24. Eligible applicants include both extramural and intramural organizations, focusing on innovative research addressing specific areas within multiple sclerosis (MS) such as central nervous system repair, correlates of disease activity, and symptom biology. Pre-application submissions are due by June 10, 2024, with full application deadlines set for October 7, 2024. The award total costs must not exceed $1 million over a maximum performance period of three years, excluding clinical trials. Applications are evaluated based on technical merit, including research strategy, feasibility, and potential impact. The review process consists of peer and programmatic evaluations to align funded projects with DOD objectives. This initiative represents the DOD's commitment to advancing MS research and improving patient care through innovative scientific approaches.
    Similar Opportunities
    DoD Reconstructive Transplant Research, Investigator-Initiated Research Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is inviting applications for the FY24 Reconstructive Transplant Research Program (RTRP) Investigator-Initiated Research Award, aimed at advancing reconstructive transplant research and improving healthcare for military service members and veterans. This grant opportunity seeks proposals that focus on vascularized composite allotransplantation (VCA) and immunotherapy, emphasizing the optimization of immunosuppressive techniques, identification of noninvasive biomarkers for graft rejection monitoring, and development of tissue preservation strategies. With an estimated total program funding of $4 million, individual principal investigator applications can receive up to $1 million, while multiple principal investigator collaborations may secure up to $1.5 million, contingent upon successful peer review. The pre-application deadline is August 7, 2024, and the full application deadline is October 23, 2024. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.
    DoD Arthritis, Focused Research Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the DoD Arthritis Focused Research Award (Funding Opportunity Number: HT942524ATRPFRA) to support innovative research aimed at improving patient care for individuals affected by arthritis. This grant encourages applications that explore high-risk, high-reward research addressing various types of arthritis, including osteoarthritis and rheumatoid arthritis, with a particular focus on the implications for military personnel and their families. The total funding available for FY24 is approximately $2.5 million, with individual project budgets capped at $750,000 for Research Level 2 and $500,000 for Research Level 1. Interested applicants must submit a pre-application by October 16, 2024, and a full application by October 30, 2024, and can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.
    DoD Arthritis Research, Clinical Research Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Materiel Command (USAMRAA), is offering the FY24 Arthritis Research Clinical Research Award (ATRP CRA) to support clinical research aimed at improving the understanding and management of various forms of arthritis, particularly in military personnel and their families. This grant program encourages innovative research proposals that address disease-specific factors and interventions, with a focus on enhancing patient outcomes and informing clinical care or policy. With an estimated total funding of $6 million, the program anticipates awarding approximately three grants, including one for a clinical trial, with applications due by October 30, 2024, and a pre-application deadline of October 16, 2024. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.
    Toxic Exposures Investigator-Initiated Research Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Toxic Exposures Investigator-Initiated Research Award (TERP IIRA) to support research addressing health outcomes related to military-related toxic exposures. This grant aims to fund studies that contribute significantly to understanding and improving patient care for diseases associated with such exposures, encompassing all research phases from basic laboratory studies to translational research involving human subjects and animal models. With an estimated total program funding of $3.2 million and the expectation of awarding four grants, interested applicants must submit pre-applications by August 13, 2024, and full applications by November 7, 2024. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD VRP, Investigator-Initiated Research Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY24 Vision Research Program (VRP) Investigator-Initiated Research Award, aimed at advancing research on eye injuries related to military service. This grant opportunity seeks innovative proposals that address the understanding, prevention, diagnosis, and treatment of eye injuries associated with military exposure, with two funding levels available to accommodate projects at different stages of maturity. The program emphasizes the importance of improving care for service members and veterans affected by visual injuries, with an estimated total funding of $832,000 and the expectation of awarding approximately seven grants. Interested applicants must submit a pre-application by July 11, 2024, followed by a full application due by November 8, 2024; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD VRP, Clinical Trial Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research Acquisition Activity (USAMRAA), is offering the FY24 Vision Clinical Trial Award to fund innovative clinical trials aimed at addressing eye injuries and visual dysfunctions related to military service. This grant opportunity supports early-phase clinical trials that evaluate new products, pharmacologic agents, and devices, with a focus on improving treatment outcomes for service-connected visual impairments. With an estimated total program funding of $2.56 million and an anticipated award amount of up to $1.6 million per application, interested applicants must submit their pre-applications by July 11, 2024, and full applications by November 8, 2024. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD USAMRDC FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the U.S. Army Medical Research and Development Command (USAMRDC), has announced the FY23-FY27 Broad Agency Announcement (BAA) for Extramural Medical Research, which is open for submissions from October 1, 2022, to September 30, 2027. This opportunity invites innovative research proposals that address critical military medical challenges, particularly in the areas of Military Infectious Diseases, Combat Casualty Care, and Military Operational Medicine, with a focus on enhancing medical practices for both military personnel and civilians. The BAA emphasizes the importance of collaboration with Department of Defense and Department of Veterans Affairs resources and requires adherence to strict submission guidelines via Grants.gov and the electronic Biomedical Research Application Portal (eBRAP). Interested applicants can submit pre-proposals at any time during the five-year period, with full proposals invited based on initial submissions, and should direct inquiries to the CDMRP Help Desk at help@eBRAP.org.
    DoD Reconstructive Transplant, Idea Discovery Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Materiel Command (USAMRAA), is offering the FY24 Reconstructive Transplant Idea Discovery Award, a federal grant aimed at supporting innovative and high-risk research in reconstructive transplant and immunotherapy. This grant seeks to generate robust data that can lead to new scientific investigations, particularly focusing on enhancing immunosuppression techniques and advancing tissue preservation strategies relevant to military personnel and veterans. With an estimated total program funding of $2.5 million, the award will provide up to $500,000 for each selected project over a two-year period, contingent upon the availability of federal funds and the merit of applications. Interested applicants must submit a pre-application by August 7, 2024, followed by a full application due by October 23, 2024; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD VRP, Translational Research Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY24 Vision Translational Research Award (VRP TRA) to support innovative translational research aimed at advancing the prevention, diagnosis, and treatment of eye injuries and visual dysfunction associated with military service. This grant opportunity encourages projects that establish a clear path for transforming promising discoveries into clinical applications, including new drugs and devices, with a focus on collaboration with regulatory experts to facilitate the approval process. With an estimated total program funding of $1.6 million and the expectation of one award, interested applicants must submit a pre-application by July 11, 2024, followed by a full application by November 8, 2024. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Reconstructive Transplant, Advanced Technology Development Award
    Active
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY24 Reconstructive Transplant Advanced Technology Development Award, aimed at supporting innovative research in reconstructive transplantation for injured Service Members and Veterans. This grant opportunity encourages the development of products such as drugs, biologic agents, and clinical practice guidelines, with a focus on enhancing techniques and access to reconstructive transplantation. The program has an estimated total funding of $3.5 million, with awards of up to $1.5 million available for applications involving multiple principal investigators. Interested applicants must submit a pre-application by August 7, 2024, followed by a full application due by October 23, 2024; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.