DoD Multiple Sclerosis, Investigator-Initiated Research Award
ID: 353638Type: Posted
Overview

Buyer

Dept. of the Army -- USAMRAA (DOD-AMRAA)

Eligible Applicants

Unrestricted

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/353638
Timeline
    Description

    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY24 Multiple Sclerosis Investigator-Initiated Research Award (IIRA) to support high-impact research projects related to multiple sclerosis (MS). This funding opportunity aims to advance innovative research that addresses critical areas within MS, such as central nervous system repair and disease activity correlates, with a total program funding of $6 million and an expected six awards. The initiative is particularly significant for enhancing patient care and quality of life for active duty military personnel, veterans, and the public. Interested applicants must submit pre-applications by June 10, 2024, with full applications due by October 7, 2024; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.

    Point(s) of Contact
    help@eBRAP.org
    Files
    Title
    Posted
    HT942524MSRPIIRA_GG.pdf
    HT942524MSRPIIRA_GG2.pdf
    The Department of Defense (DOD) is announcing the FY24 Multiple Sclerosis Investigator-Initiated Research Award (IIRA) under the Congressionally Directed Medical Research Programs. This funding opportunity aims to support high-impact research relevant to active duty military personnel, veterans, and the public, with a total appropriation of $20 million for FY24. Eligible applicants include both extramural and intramural organizations, focusing on innovative research addressing specific areas within multiple sclerosis (MS) such as central nervous system repair, correlates of disease activity, and symptom biology. Pre-application submissions are due by June 10, 2024, with full application deadlines set for October 7, 2024. The award total costs must not exceed $1 million over a maximum performance period of three years, excluding clinical trials. Applications are evaluated based on technical merit, including research strategy, feasibility, and potential impact. The review process consists of peer and programmatic evaluations to align funded projects with DOD objectives. This initiative represents the DOD's commitment to advancing MS research and improving patient care through innovative scientific approaches.
    Similar Opportunities
    DoD Toxic Exposures Investigator-Initiated Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Toxic Exposures Investigator-Initiated Research Award (IIRA) to support research on military-related toxic exposures and their health impacts. This grant aims to fund studies across various research phases, including basic laboratory research, translational research, and preclinical studies, with a total estimated funding of approximately $3.85 million to support around five projects, each receiving a maximum of $770,000 over three years. The program is crucial for advancing understanding and treatment of health conditions associated with toxic exposures faced by service members and veterans. Interested applicants, including both domestic and foreign organizations, must submit pre-applications by July 29, 2025, with full applications due by October 16, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Peer Reviewed Medical Research Program, Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity under the Peer Reviewed Medical Research Program (PRMRP) for the fiscal year 2025, specifically for the Clinical Trial Award (CTA). This program aims to support the rapid implementation of clinical trials that can significantly impact the treatment or management of diseases relevant to military health, with a focus on areas such as autoimmune disorders, cardiovascular health, infectious diseases, and neuroscience. Approximately $32 million is available for this initiative, with an expected four awards, each capped at $8 million, and applications are due by July 21, 2025. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507 for further assistance.
    Alzheimer’s Research Program Transforming Care Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Alzheimer's Research Program Transforming Care Award to support innovative clinical research aimed at improving care for individuals with Alzheimer's disease and related dementias (AD/ADRD). This funding opportunity encourages community collaboration and requires projects to focus on interventions that enhance the quality of life for both patients and their caregivers. Approximately $5.2 million is available to fund around three awards, with pre-applications due by June 12, 2025, and full applications due by August 29, 2025. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.
    Alzheimer’s Research Program Transforming Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Alzheimer's Research Program Transforming Research Award to support innovative research aimed at reducing the risk of Alzheimer's disease and related dementias (AD/ADRD). This grant opportunity encourages diverse applicants, including for-profit, non-profit, and academic institutions, and emphasizes the necessity of community collaboration, particularly for clinical research projects. With an estimated total program funding of $4 million, the program anticipates awarding approximately four grants, each providing up to $1 million over a maximum of three years. Interested applicants must submit a pre-application by June 12, 2025, followed by a full application due by August 29, 2025. For further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Amyotrophic Lateral Sclerosis, Therapeutic Idea Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Therapeutic Idea Award (TIA) under the fiscal year 2025 Amyotrophic Lateral Sclerosis Research Program (ALSRP). This grant aims to support innovative, high-risk research proposals focused on drug or therapy development for Amyotrophic Lateral Sclerosis (ALS), with an emphasis on generating preliminary data for future therapeutic investigations. The program has a total funding amount of approximately $10.8 million, with individual awards capped at $600,000 and a performance period not exceeding two years. Interested applicants must submit pre-applications by June 6, 2025, and full applications by August 27, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Military Burn, Patient-Centered Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Military Burn Research Program's Patient-Centered Research Award (PCRA) to enhance clinical practices and interventions for burn victims in combat conditions. This grant opportunity, with an estimated total funding of $3.4 million, specifically supports clinical research involving human subjects, excluding preclinical studies, and aims to bridge the gap between research and practical application in austere environments. Proposals should focus on improving acute burn care practices, developing methods to prevent and treat cold injuries, and managing complications such as fluid resuscitation and inhalation injuries, with a strong emphasis on military health relevance and potential impact. Interested applicants must submit pre-applications by June 23, 2025, and full applications by September 8, 2025, with funding announcements expected by September 30, 2026. For further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD USAMRDC FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the U.S. Army Medical Research and Development Command (USAMRDC), has announced the FY23-FY27 Broad Agency Announcement (BAA) for Extramural Medical Research, which is open for submissions from October 1, 2022, to September 30, 2027. This opportunity invites innovative research proposals that address critical military medical challenges, particularly in the areas of Military Infectious Diseases, Combat Casualty Care, and Military Operational Medicine, with a focus on enhancing medical practices for both military personnel and civilians. The BAA emphasizes the importance of collaboration with Department of Defense and Department of Veterans Affairs resources and requires adherence to strict submission guidelines via Grants.gov and the electronic Biomedical Research Application Portal (eBRAP). Interested applicants can submit pre-proposals at any time during the five-year period, with full proposals invited based on initial submissions, and should direct inquiries to the CDMRP Help Desk at help@eBRAP.org.
    DoD Melanoma, Idea Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Melanoma Research Program Idea Award to support innovative and exploratory research related to melanoma. This grant aims to fund high-risk, potentially high-reward projects that focus on areas such as melanoma prevention, rare melanoma research, or survivorship impacts, with a maximum direct cost of $400,000 available for each project over a two-year period. The program is particularly significant for advancing melanoma detection, treatment, and survivorship, especially in the context of military health concerns. Interested applicants must submit a pre-application by June 30, 2025, followed by a full application due by October 1, 2025, with a total funding pool of approximately $5.76 million available for about nine awards. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Amyotrophic Lateral Sclerosis, Pilot Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Amyotrophic Lateral Sclerosis Research Program (ALSRP) Pilot Clinical Trial Award to support clinical trials aimed at improving the treatment and management of Amyotrophic Lateral Sclerosis (ALS). Applicants are required to focus on either biomarker-driven interventions or enhancements in clinical care, with an emphasis on incorporating community collaboration to optimize research impact. This funding opportunity allocates approximately $6.6 million to support around two pilot clinical trial applications, with a direct cost cap of $2 million for each project. Interested parties must submit a pre-application by June 6, 2025, followed by a full application due on August 27, 2025. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.
    Alzheimer’s Research Program Transforming Diagnosis Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Alzheimer's Research Program Transforming Diagnosis Award to support innovative research aimed at enhancing the diagnosis and prognosis of Alzheimer's disease and related dementias (AD/ADRD). This grant opportunity encourages community collaboration and requires the submission of preliminary data, with a focus on addressing barriers to effective dementia diagnosis. With an estimated total program funding of $3.2 million, the program anticipates awarding two grants, with funding caps set at $1.5 million for single Principal Investigator (PI) proposals and $1.7 million for those utilizing the Career Initiation or Transition Partnership Option. Interested applicants must submit a pre-application by June 12, 2025, followed by a full application due by August 29, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.