Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)
Grant Opportunity Analysis
The National Institutes of Health (NIH) is inviting applications for the Cancer Intervention and Surveillance Modeling Network (CISNET) through a Notice of Funding Opportunity (NOFO) aimed at collaborative research projects utilizing simulation and modeling techniques for specific cancer types. The primary objective is to develop evidence-based tools that inform efficient strategies for cancer control, focusing on comparative modeling for cancers such as bladder, breast, cervix, colon/rectum, esophagus, gastric, multiple myeloma, lung, prostate, and uterine. This initiative is crucial for enhancing cancer control efforts and improving outcomes in at-risk populations. The NIH plans to allocate approximately $9.438 million in FY 2026 to fund up to eight awards, with applications due by February 11, 2026. Interested applicants can reach out to Natasha Stout at natasha.stout@nih.gov for further information.
Eligible Applicants
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Applications Involving the NIH Intramural Research ProgramThe requests by NIH intramural scientists will be limited to the incremental costs required for participation. As such, these requests will not include any salary and related fringe benefits for career, career conditional or other Federal employees (civilian or uniformed service) with permanent appointments under existing position ceilings or any costs related to administrative or facilities support (equivalent to Facilities and Administrative or F&A costs). These costs may include salary for staff to be specifically hired under a temporary appointment for the project, consultant costs, equipment, supplies, travel, and other items typically listed under Other Expenses. Applicants should indicate the number of person-months devoted to the project, even if no funds are requested for salary and fringe benefits.If selected, appropriate funding will be provided by the NIH Intramural Program. Intellectual property will be managed in accord with established policy of NIH in compliance with Executive Order 10096, as amended, 45 CFR Part 7; patent rights for inventions developed in NIH facilities are NIH property unless NIH waives its rights.Should an extramural application include the collaboration with an intramural scientist, no funds for the support of the intramural scientist may be requested in the application. The intramural scientist may submit a separate request for intramural funding as described above.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.