The Department of Defense's Fiscal Year 2025 (FY25) Breast Cancer Research Program (BCRP) Clinical Research Extension Award aims to enhance the impact of breast cancer clinical studies by expanding data collection and analysis. Approximately $26.35 million is allocated to fund around three projects, with direct cost caps of $5 million for single Principal Investigators (PIs) and $6 million for those applying as partnered PIs. Eligible applicants include various organizations, both domestic and foreign, with a requirement for involvement from at least two breast cancer consumer advocates. The award seeks to address critical challenges in breast cancer research, including prevention, understanding cancer behavior, and improving treatment regimens. Research proposals should demonstrate scientific merit, including a solid rationale backed by preliminary data and a detailed data-sharing plan. The application process involves a two-step submission: a pre-application due by June 13, 2025, followed by a full application by June 27, 2025. Applications will undergo a peer review process focusing on impact, research strategy, personnel qualifications, and partnership dynamics when applicable. Successful applicants will receive notification within six weeks after the programmatic review of their proposals.