The National Institutes of Health (NIH) is set to publish a Notice of Funding Opportunity (NOFO) for the renewal of the Adult-Adolescent Brain Cognitive Development (A-ABCD) Study, specifically for research project sites under the U01 cooperative agreement mechanism. This initiative aims to continue the groundbreaking ABCD study, which is the largest long-term investigation of brain development and child and adolescent health in the U.S., by following the original cohort of nearly 12,000 participants into their emerging adulthood to assess various health outcomes. The study utilizes advanced technologies, including brain scans and wearable sensors, to explore how young adult experiences influence brain development and related social and health outcomes. Interested organizations that were funded through RFA-DA-20-002 are encouraged to prepare for this opportunity, with the estimated synopsis posting date on February 6, 2026, and a projected award date of April 1, 2027. For further inquiries, potential applicants can contact Dr. Bethany Deeds at deedsb@nida.nih.gov or by phone at 301-402-1935.