The National Science Foundation (NSF) is offering a grant opportunity titled "Computational and Data-Enabled Science and Engineering" aimed at advancing scientific and engineering breakthroughs through innovative computational and data-analysis approaches. This program encourages proposals that significantly leverage computational or data science to address complex scientific challenges, with an emphasis on interdisciplinary research that may span multiple divisions and directorates within the NSF. Proposals can be submitted at any time, with specific submission windows for various divisions outlined, and interested applicants can reach out to NSF grants.gov support at grantsgovsupport@nsf.gov for assistance. For more details, applicants are encouraged to visit the NSF program description at http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=506212.